Identity
HGNC
LOCATION
20p13
LOCUSID
ALIAS
ASCR,AltPrP,CD230,CJD,GSS,KURU,PRIP,PrP,PrP27-30,PrP33-35C,PrPc,p27-30
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5621
MIM: 176640
HGNC: 9449
Ensembl: ENSG00000171867
Variants:
dbSNP: 5621
ClinVar: 5621
TCGA: ENSG00000171867
COSMIC: PRNP
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37669322 | 2024 | Cross-seeding by prion protein inactivates TDP-43. | 3 |
| 37689591 | 2024 | Pooled analysis of patients with inherited prion disease caused by two- to twelve-octapeptide repeat insertions in the prion protein gene (PRNP). | 0 |
| 38347462 | 2024 | Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomas. | 0 |
| 38474214 | 2024 | New Light on Prions: Putative Role of PrP(c) in Pathophysiology of Mood Disorders. | 0 |
| 39048735 | 2024 | Neuropathologically directed profiling of PRNP somatic and germline variants in sporadic human prion disease. | 0 |
| 37669322 | 2024 | Cross-seeding by prion protein inactivates TDP-43. | 3 |
| 37689591 | 2024 | Pooled analysis of patients with inherited prion disease caused by two- to twelve-octapeptide repeat insertions in the prion protein gene (PRNP). | 0 |
| 38347462 | 2024 | Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomas. | 0 |
| 38474214 | 2024 | New Light on Prions: Putative Role of PrP(c) in Pathophysiology of Mood Disorders. | 0 |
| 39048735 | 2024 | Neuropathologically directed profiling of PRNP somatic and germline variants in sporadic human prion disease. | 0 |
| 35176965 | 2023 | Simulation analysis of selective alanine mutation effect on stability of human prion protein. | 0 |
| 36744645 | 2023 | PRNP expression predicts imaging findings in sporadic Creutzfeldt-Jakob disease. | 2 |
| 36843471 | 2023 | [Gerstmann-Sträussler disease: a familial case with common PRNP mutation and atypical features]. | 0 |
| 36879070 | 2023 | A point mutation in GPI-attachment signal peptide accelerates the development of prion disease. | 0 |
| 36939723 | 2023 | Bilateral tonic-clonic seizure and focal cortical hyperexcitability in familial Creutzfeldt-Jakob disease with E200K mutation of the prion protein. | 0 |
Citation
Dessen P
PRNP (prion protein)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/50612/prnp-(prion-protein)
