EMB (embigin)

2009-01-01 Affiliation

Identity

HGNC

EMB

LOCATION

5q11.1

LOCUSID

133418

ALIAS

GP70

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 133418
MIM: 615669
HGNC: 30465
Ensembl: ENSG00000170571

Variants:

dbSNP: 133418
ClinVar: 133418
TCGA: ENSG00000170571
COSMIC: EMB

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000170571	ENST00000303221	Q6PCB8
ENSG00000170571	ENST00000508934	D6RDX7
ENSG00000170571	ENST00000514111	Q6PCB8

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Transmembrane transport of small molecules	REACTOME	R-HSA-382551
SLC-mediated transmembrane transport	REACTOME	R-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	REACTOME	R-HSA-425366
Proton-coupled monocarboxylate transport	REACTOME	R-HSA-433692

References

Pubmed ID	Year	Title	Citations
32213169	2020	Rare and common variants analysis of the EMB gene in patients with schizophrenia.	3
32213169	2020	Rare and common variants analysis of the EMB gene in patients with schizophrenia.	3
30446621	2019	Membrane-anchored carbonic anhydrase IV interacts with monocarboxylate transporters via their chaperones CD147 and GP70.	17
30446621	2019	Membrane-anchored carbonic anhydrase IV interacts with monocarboxylate transporters via their chaperones CD147 and GP70.	17
25773908	2016	Embigin is overexpressed in pancreatic ductal adenocarcinoma and regulates cell motility through epithelial to mesenchymal transition via the TGF-β pathway.	12
25773908	2016	Embigin is overexpressed in pancreatic ductal adenocarcinoma and regulates cell motility through epithelial to mesenchymal transition via the TGF-β pathway.	12
26090721	2015	Embigin, regulated by HOXC8, plays a suppressive role in breast tumorigenesis.	13
26090721	2015	Embigin, regulated by HOXC8, plays a suppressive role in breast tumorigenesis.	13
21787388	2011	Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.	80
21787388	2011	Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.	80
2963822	1988	A teratocarcinoma glycoprotein carrying a developmentally regulated carbohydrate marker is a member of the immunoglobulin gene superfamily.	12
2963822	1988	A teratocarcinoma glycoprotein carrying a developmentally regulated carbohydrate marker is a member of the immunoglobulin gene superfamily.	12

Citation

Dessen P

EMB (embigin)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50617/gene-explorer/gene-fusions-explorer/humanGenome