RGS22 (regulator of G protein signaling 22)

2009-01-01  

Identity

HGNC
RGS22
LOCATION
8q22.2
LOCUSID
26166
ALIAS
CT145,PRTD-NY2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26166
MIM: 615650
HGNC: 24499
Ensembl: ENSG00000132554

Variants:

dbSNP: 26166
ClinVar: 26166
TCGA: ENSG00000132554
COSMIC: RGS22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132554ENST00000360863Q8NE09
ENSG00000132554ENST00000517828E5RGJ7
ENSG00000132554ENST00000517843H0YBV2
ENSG00000132554ENST00000519092E5RHE4
ENSG00000132554ENST00000519408E5RFV6
ENSG00000132554ENST00000519725Q8NE09
ENSG00000132554ENST00000520117E5RJ23
ENSG00000132554ENST00000523287G3V112
ENSG00000132554ENST00000523437Q8NE09
ENSG00000132554ENST00000617334A0A087WV61

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

References

Pubmed IDYearTitleCitations
290389252018miR-1260b promotes cell migration and invasion of hepatocellular carcinoma by targeting the regulator of G-protein signaling 22.11
290389252018miR-1260b promotes cell migration and invasion of hepatocellular carcinoma by targeting the regulator of G-protein signaling 22.11
263232642015RGS22 inhibits pancreatic adenocarcinoma cell migration through the G12/13 α subunit/F-actin pathway.10
263232642015RGS22 inhibits pancreatic adenocarcinoma cell migration through the G12/13 α subunit/F-actin pathway.10
244030522014Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.30
244030522014Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.30
215338722011RGS22, a novel cancer/testis antigen, inhibits epithelial cell invasion and metastasis.13
215338722011RGS22, a novel cancer/testis antigen, inhibits epithelial cell invasion and metastasis.13
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206278712010Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.7
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206278712010Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.7
187034242008RGS22, a novel testis-specific regulator of G-protein signaling involved in human and mouse spermiogenesis along with GNA12/13 subunits.11
187034242008RGS22, a novel testis-specific regulator of G-protein signaling involved in human and mouse spermiogenesis along with GNA12/13 subunits.11

Citation

Dessen P

RGS22 (regulator of G protein signaling 22)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50620/rgs22-(regulator-of-g-protein-signaling-22)