EMP2 (epithelial membrane protein 2)

2009-01-01  

Identity

HGNC
LOCATION
16p13.13
LOCUSID
ALIAS
XMP
FUSION GENES

Other Information

Locus ID:

NCBI: 2013
MIM: 602334
HGNC: 3334
Ensembl: ENSG00000213853

Variants:

dbSNP: 2013
ClinVar: 2013
TCGA: ENSG00000213853
COSMIC: EMP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000213853ENST00000359543P54851
ENSG00000213853ENST00000536829P54851

Expression (GTEx)

0
50
100
150
200
250
300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
248141932014Mutations in EMP2 cause childhood-onset nephrotic syndrome.34
162162332005Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium.33
127109412003Epithelial membrane protein-2 is expressed in discrete anatomical regions of the eye.25
176092062007The tetraspan protein EMP2 regulates expression of caveolin-1.23
216377652011Epithelial membrane protein-2 promotes endometrial tumor formation through activation of FAK and Src.19
233343312013EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF.18
259407042015The cAMP responsive element binding protein 1 transactivates epithelial membrane protein 2, a potential tumor suppressor in the urinary bladder urothelial carcinoma.17
190108522008Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines.15
206709492010Epithelial membrane protein-2 is a novel therapeutic target in ovarian cancer.15
184001072008Steroid hormone regulation of EMP2 expression and localization in the endometrium.14

Citation

Dessen P

EMP2 (epithelial membrane protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50637/emp2-(epithelial-membrane-protein-2)