CAB39L (calcium binding protein 39 like)

2009-01-01  

Identity

HGNC
CAB39L
LOCATION
13q14.2
LOCUSID
81617
ALIAS
MO25-BETA,MO2L,bA103J18.3

Other Information

Locus ID:

NCBI: 81617
MIM: 612175
HGNC: 20290
Ensembl: ENSG00000102547

Variants:

dbSNP: 81617
ClinVar: 81617
TCGA: ENSG00000102547
COSMIC: CAB39L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102547ENST00000347776Q9H9S4
ENSG00000102547ENST00000347776A0A024RDT3
ENSG00000102547ENST00000355854Q9H9S4
ENSG00000102547ENST00000355854A0A024RDT3
ENSG00000102547ENST00000409082B7ZBJ7
ENSG00000102547ENST00000409130B7ZBJ4
ENSG00000102547ENST00000409308Q9H9S4
ENSG00000102547ENST00000409308A0A024RDT3
ENSG00000102547ENST00000410043Q9H9S4
ENSG00000102547ENST00000410043A0A024RDT3
ENSG00000102547ENST00000413278B7ZBJ6
ENSG00000102547ENST00000425242Q5TAW7
ENSG00000102547ENST00000457041B7ZBJ5
ENSG00000102547ENST00000610540Q9H9S4
ENSG00000102547ENST00000610540A0A024RDT3

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
mTOR signaling pathwayKEGGko04150
mTOR signaling pathwayKEGGhsa04150
AMPK signaling pathwayKEGGhsa04152
AMPK signaling pathwayKEGGko04152
Signal TransductionREACTOMER-HSA-162582
Signaling by Insulin receptorREACTOMER-HSA-74752
Insulin receptor signalling cascadeREACTOMER-HSA-74751
IRS-mediated signallingREACTOMER-HSA-112399
PI3K CascadeREACTOMER-HSA-109704
PKB-mediated eventsREACTOMER-HSA-109703
mTOR signallingREACTOMER-HSA-165159
Energy dependent regulation of mTOR by LKB1-AMPKREACTOMER-HSA-380972
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)REACTOMER-HSA-2404192
IGF1R signaling cascadeREACTOMER-HSA-2428924
IRS-related events triggered by IGF1RREACTOMER-HSA-2428928

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
300545622018CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis.8
185922352009Identification and functional characterization of the novel acute monocytic leukemia associated antigen MLAA-34.7
212404832011Quantitative assessment of MLAA-34 expression in diagnosis and prognosis of acute monocytic leukemia.6
231356222013The expression and functional characterization associated with cell apoptosis and proteomic analysis of the novel gene MLAA-34 in U937 cells.5
263064672016Frameshift Mutations of CAB39L, an Activator of LKB1 Tumor Suppressor, in Gastric and Colorectal Cancers.1
312049112019[Cloning of New Antigen Gene MLAA-34 Promoter and Identification of Core Region in Acute Monocytic Leukemia].0

Citation

Dessen P

CAB39L (calcium binding protein 39 like)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50657/cab39l-(calcium-binding-protein-39-like)