SRPX2 (sushi repeat containing protein X-linked 2)

2009-02-01  

Identity

HGNC
LOCATION
Xq22.1
LOCUSID
ALIAS
BPP,CBPS,PMGX,RESDX,SRPUL

Other Information

Locus ID:

NCBI: 27286
MIM: 300642
HGNC: 30668
Ensembl: ENSG00000102359

Variants:

dbSNP: 27286
ClinVar: 27286
TCGA: ENSG00000102359
COSMIC: SRPX2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102359ENST00000373004O60687
ENSG00000102359ENST00000638458A0A1W2PR88
ENSG00000102359ENST00000640282A0A1W2PNZ6
ENSG00000102359ENST00000640889A0A1W2PRB1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373068722023SRPX2 promotes cancer cell proliferation and migration of papillary thyroid cancer.0
373068722023SRPX2 promotes cancer cell proliferation and migration of papillary thyroid cancer.0
340938742021Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition.20
340938742021Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition.20
324558672020Sushi Repeat Containing Protein X-linked 2 Is a Downstream Signal of LEM Domain Containing 1 and Acts as a Tumor-Promoting Factor in Oral Squamous Cell Carcinoma.8
325507002020SRPX2 promotes cell proliferation and invasion via activating FAK/SRC/ERK pathway in non-small cell lung cancer.8
324558672020Sushi Repeat Containing Protein X-linked 2 Is a Downstream Signal of LEM Domain Containing 1 and Acts as a Tumor-Promoting Factor in Oral Squamous Cell Carcinoma.8
325507002020SRPX2 promotes cell proliferation and invasion via activating FAK/SRC/ERK pathway in non-small cell lung cancer.8
303931912019Exploring the association between SRPX2 variants and neurodevelopment: How causal is it?7
305515192019SRPX2 knockdown inhibits cell proliferation and metastasis and promotes chemosensitivity in esophageal squamous cell carcinoma.15
303931912019Exploring the association between SRPX2 variants and neurodevelopment: How causal is it?7
305515192019SRPX2 knockdown inhibits cell proliferation and metastasis and promotes chemosensitivity in esophageal squamous cell carcinoma.15
286547962017SRPX2, an independent prognostic marker, promotes cell migration and invasion in hepatocellular carcinoma.11
288677542017Sushi repeat-containing protein X-linked 2 promotes angiogenesis through the urokinase-type plasminogen activator receptor dependent integrin αvβ3/focal adhesion kinase pathways.10
286547962017SRPX2, an independent prognostic marker, promotes cell migration and invasion in hepatocellular carcinoma.11

Citation

Dessen P

SRPX2 (sushi repeat containing protein X-linked 2)

Atlas Genet Cytogenet Oncol Haematol. 2009-02-01

Online version: http://atlasgeneticsoncology.org/gene/50677/srpx2-(sushi-repeat-containing-protein-x-linked-2)/