Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55715
MIM: 608333
HGNC: 19868
Ensembl: ENSG00000125170
Variants:
dbSNP: 55715
ClinVar: 55715
TCGA: ENSG00000125170
COSMIC: DOK4
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Axon guidance | REACTOME | R-HSA-422475 |
| RET signaling | REACTOME | R-HSA-8853659 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32386480 | 2020 | Study of DOK4 gene expression and promoter methylation in sporadic breast cancer. | 2 |
| 32386480 | 2020 | Study of DOK4 gene expression and promoter methylation in sporadic breast cancer. | 2 |
| 22982678 | 2012 | New insights into Dok-4 PTB domain structure and function. | 3 |
| 22982678 | 2012 | New insights into Dok-4 PTB domain structure and function. | 3 |
| 19494292 | 2009 | Dok-4 is a novel negative regulator of T cell activation. | 8 |
| 19494292 | 2009 | Dok-4 is a novel negative regulator of T cell activation. | 8 |
| 19073520 | 2008 | Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells. | 4 |
| 19073520 | 2008 | Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells. | 4 |
| 17443497 | 2007 | DOK4/IRS-5 expression is altered in clear cell renal cell carcinoma. | 4 |
| 17443497 | 2007 | DOK4/IRS-5 expression is altered in clear cell renal cell carcinoma. | 4 |
| 16820412 | 2006 | Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase. | 22 |
| 16820412 | 2006 | Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase. | 22 |
| 12595900 | 2003 | DOK4 and DOK5: new Dok-related genes expressed in human T cells. | 16 |
| 12730241 | 2003 | Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5. | 68 |
| 12595900 | 2003 | DOK4 and DOK5: new Dok-related genes expressed in human T cells. | 16 |
Citation
Dessen P
DOK4 (docking protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2009-03-01
Online version: http://atlasgeneticsoncology.org/gene/50679/dok4-(docking-protein-4)
