Identity
HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
HAP2,HIP5,HLP,hHLP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9001
MIM: 600947
HGNC: 4812
Ensembl: ENSG00000173805
Variants:
dbSNP: 9001
ClinVar: 9001
TCGA: ENSG00000173805
COSMIC: HAP1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Huntington's disease | KEGG | ko05016 |
| Huntington's disease | KEGG | hsa05016 |
| GABAergic synapse | KEGG | ko04727 |
| GABAergic synapse | KEGG | hsa04727 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36509909 | 2023 | Huntingtin-associated protein 1 is a potential tumor suppressor for gastric cancer. | 3 |
| 36509909 | 2023 | Huntingtin-associated protein 1 is a potential tumor suppressor for gastric cancer. | 3 |
| 36251080 | 2022 | Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains. | 4 |
| 36251080 | 2022 | Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains. | 4 |
| 34014261 | 2021 | Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway. | 47 |
| 34014261 | 2021 | Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway. | 47 |
| 33184093 | 2020 | Efficient and crucial quality control of HAP1 cell ploidy status. | 18 |
| 33184093 | 2020 | Efficient and crucial quality control of HAP1 cell ploidy status. | 18 |
| 30560333 | 2019 | Expression and Localization of Huntingtin-Associated Protein 1 (HAP1) in the Human Digestive System. | 4 |
| 30819925 | 2019 | HAP1 loss confers l-asparaginase resistance in ALL by downregulating the calpain-1-Bid-caspase-3/12 pathway. | 19 |
| 31757889 | 2019 | The adaptor proteins HAP1a and GRIP1 collaborate to activate the kinesin-1 isoform KIF5C. | 27 |
| 30560333 | 2019 | Expression and Localization of Huntingtin-Associated Protein 1 (HAP1) in the Human Digestive System. | 4 |
| 30819925 | 2019 | HAP1 loss confers l-asparaginase resistance in ALL by downregulating the calpain-1-Bid-caspase-3/12 pathway. | 19 |
| 31757889 | 2019 | The adaptor proteins HAP1a and GRIP1 collaborate to activate the kinesin-1 isoform KIF5C. | 27 |
| 27737633 | 2016 | Huntingtin-associated protein 1: Eutherian adaptation from a TRAK-like protein, conserved gene promoter elements, and localization in the human intestine. | 3 |
Citation
Dessen P
HAP1 (huntingtin associated protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-03-01
Online version: http://atlasgeneticsoncology.org/gene/50706/hap1-(huntingtin-associated-protein-1)
