FHL3 (four and a half LIM domains 3)

2009-03-01  

Identity

HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
SLIM2
FUSION GENES

Other Information

Locus ID:

NCBI: 2275
MIM: 602790
HGNC: 3704
Ensembl: ENSG00000183386

Variants:

dbSNP: 2275
ClinVar: 2275
TCGA: ENSG00000183386
COSMIC: FHL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183386ENST00000373016Q13643

Expression (GTEx)

0
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300
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800
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1000

References

Pubmed IDYearTitleCitations
191395642009Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway.59
151179622004The LIM-only proteins FHL2 and FHL3 interact with alpha- and beta-subunits of the muscle alpha7beta1 integrin receptor.32
173896852007FHL3 binds MyoD and negatively regulates myotube formation.22
222191852012Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1.21
256590962015Angiogenin promotes U87MG cell proliferation by activating NF-κB signaling pathway and downregulating its binding partner FHL3.9
154538302005FHL3 negatively regulates human high-affinity IgE receptor beta-chain gene expression by acting as a transcriptional co-repressor of MZF-1.8
226338742012Identification and characterization of FHL3 as a novel angiogenin-binding partner.6
223627142011Downregulation and antiproliferative role of FHL3 in breast cancer.5
126812902003LIM-only protein FHL3 interacts with CDC25B2 phosphatase.2
205861942010Identification of the transactivation domain of the human FHL3.1

Citation

Dessen P

FHL3 (four and a half LIM domains 3)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50795/fhl3-(four-and-a-half-lim-domains-3)