FHL3 (four and a half LIM domains 3)

2009-03-01  

Identity

HGNC
FHL3
LOCATION
1p34.3
LOCUSID
2275
ALIAS
SLIM2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2275
MIM: 602790
HGNC: 3704
Ensembl: ENSG00000183386

Variants:

dbSNP: 2275
ClinVar: 2275
TCGA: ENSG00000183386
COSMIC: FHL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183386ENST00000373016Q13643

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
1000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
352494712022Upregulation of FHL1, SPNS3, and MPZL2 predicts poor prognosis in pediatric acute myeloid leukemia patients with FLT3-ITD mutation.4
352494712022Upregulation of FHL1, SPNS3, and MPZL2 predicts poor prognosis in pediatric acute myeloid leukemia patients with FLT3-ITD mutation.4
316931822020PCBP2 promotes the development of glioma by regulating FHL3/TGF-β/Smad signaling pathway.14
316931822020PCBP2 promotes the development of glioma by regulating FHL3/TGF-β/Smad signaling pathway.14
299551252019FHL3 links cell growth and self-renewal by modulating SOX4 in glioma.11
299551252019FHL3 links cell growth and self-renewal by modulating SOX4 in glioma.11
256590962015Angiogenin promotes U87MG cell proliferation by activating NF-κB signaling pathway and downregulating its binding partner FHL3.14
256590962015Angiogenin promotes U87MG cell proliferation by activating NF-κB signaling pathway and downregulating its binding partner FHL3.14
246908792014Identification and characterization of MT-1X as a novel FHL3-binding partner.3
249982282014Ribotrap analysis of proteins associated with FHL3 3'untranslated region in glioma cells.1
246908792014Identification and characterization of MT-1X as a novel FHL3-binding partner.3
249982282014Ribotrap analysis of proteins associated with FHL3 3'untranslated region in glioma cells.1
236166672013The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoprotein.6
236166672013The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoprotein.6
222191852012Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1.30

Citation

Dessen P

FHL3 (four and a half LIM domains 3)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50795/gene-fusions-explorer/favicon/welcome