Identity
HGNC
LOCATION
17q21.33
LOCUSID
ALIAS
BTBD32,NEDMACE,NEDMIDF,NSDVS1,NSDVS2,TEF2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8405
MIM: 602650
HGNC: 11254
Ensembl: ENSG00000121067
Variants:
dbSNP: 8405
ClinVar: 8405
TCGA: ENSG00000121067
COSMIC: SPOP
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37327205 | 2024 | Genetic Profiling of African American Patients With Prostatic Adenocarcinoma Metastatic to the Lymph Nodes: A Pilot Study. | 0 |
| 37824367 | 2024 | The Mutational and Transcriptional Landscapes of Speckle-Type POZ Protein (SPOP) and Androgen Receptor (AR) in a Single-Center pT3 Prostatectomy Cohort. | 0 |
| 37996058 | 2024 | SPOP promotes CREB5 ubiquitination to inhibit MET signaling in liver cancer. | 0 |
| 38246227 | 2024 | Deficiency in SPOP-mediated ubiquitination and degradation of TIAM1 promotes gastric cancer progression. | 0 |
| 38308184 | 2024 | CSN6-SPOP-HMGCS1 Axis Promotes Hepatocellular Carcinoma Progression via YAP1 Activation. | 5 |
| 38340178 | 2024 | BCLAF1 binds SPOP to stabilize PD-L1 and promotes the development and immune escape of hepatocellular carcinoma. | 0 |
| 38632244 | 2024 | ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance. | 0 |
| 37327205 | 2024 | Genetic Profiling of African American Patients With Prostatic Adenocarcinoma Metastatic to the Lymph Nodes: A Pilot Study. | 0 |
| 37824367 | 2024 | The Mutational and Transcriptional Landscapes of Speckle-Type POZ Protein (SPOP) and Androgen Receptor (AR) in a Single-Center pT3 Prostatectomy Cohort. | 0 |
| 37996058 | 2024 | SPOP promotes CREB5 ubiquitination to inhibit MET signaling in liver cancer. | 0 |
| 38246227 | 2024 | Deficiency in SPOP-mediated ubiquitination and degradation of TIAM1 promotes gastric cancer progression. | 0 |
| 38308184 | 2024 | CSN6-SPOP-HMGCS1 Axis Promotes Hepatocellular Carcinoma Progression via YAP1 Activation. | 5 |
| 38340178 | 2024 | BCLAF1 binds SPOP to stabilize PD-L1 and promotes the development and immune escape of hepatocellular carcinoma. | 0 |
| 38632244 | 2024 | ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance. | 0 |
| 36481790 | 2023 | SPOP mutations promote tumor immune escape in endometrial cancer via the IRF1-PD-L1 axis. | 10 |
Citation
Dessen P
SPOP (speckle type BTB/POZ protein)
Atlas Genet Cytogenet Oncol Haematol. 2009-03-01
Online version: http://atlasgeneticsoncology.org/gene/50818
