MIR18A (microRNA 18a)

2009-03-01  

Identity

HGNC
MIR18A
LOCATION
13q31.3
LOCUSID
406953
ALIAS
C13orf25,MIR17HG,MIR18,MIRH1,MIRHG1,MIRN18,MIRN18A,hsa-mir-18,hsa-mir-18a,miR-18,miRNA18A,mir-18a

Other Information

Locus ID:

NCBI: 406953
MIM: 609417
HGNC: 31548
Ensembl: ENSG00000283815
miRBase:

Variants:

dbSNP: 406953
ClinVar: 406953
TCGA: ENSG00000283815
COSMIC: MIR18A

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
175584162007The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a.232
186326052008Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster.119
215013752011MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure.96
190270102009MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells.86
193721392009The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras.78
219804622011miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase.62
246642942014Variations of microRNAs in human placentas and plasma from preeclamptic pregnancy.59
233221972013MicroRNA-18a modulates STAT3 activity through negative regulation of PIAS3 during gastric adenocarcinogenesis.39
234373042013MicroRNA-18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancer.36
232801372013Tumor necrosis factor α-induced microRNA-18a activates rheumatoid arthritis synovial fibroblasts through a feedback loop in NF-κB signaling.31

Citation

Dessen P

MIR18A (microRNA 18a)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50824/mir18a-(microrna-18a)