Identity
HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
C1-TEN,C1TEN,TENC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23371
MIM: 607717
HGNC: 19737
Ensembl: ENSG00000111077
Variants:
dbSNP: 23371
ClinVar: 23371
TCGA: ENSG00000111077
COSMIC: TNS2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33753854 | 2021 | Novel candidate factors predicting the effect of S-1 adjuvant chemotherapy of pancreatic cancer. | 1 |
| 33753854 | 2021 | Novel candidate factors predicting the effect of S-1 adjuvant chemotherapy of pancreatic cancer. | 1 |
| 30092354 | 2018 | Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3,4,5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain. | 6 |
| 30419905 | 2018 | AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells. | 10 |
| 30092354 | 2018 | Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3,4,5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain. | 6 |
| 30419905 | 2018 | AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells. | 10 |
| 28955049 | 2017 | C1-Ten is a PTPase of nephrin, regulating podocyte hypertrophy through mTORC1 activation. | 10 |
| 28955049 | 2017 | C1-Ten is a PTPase of nephrin, regulating podocyte hypertrophy through mTORC1 activation. | 10 |
| 27203214 | 2016 | Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers. | 14 |
| 27203214 | 2016 | Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers. | 14 |
| 25101860 | 2014 | Regulation of C1-Ten protein tyrosine phosphatase by p62/SQSTM1-mediated sequestration and degradation. | 3 |
| 25101860 | 2014 | Regulation of C1-Ten protein tyrosine phosphatase by p62/SQSTM1-mediated sequestration and degradation. | 3 |
| 23233134 | 2013 | Interaction of DISC1 with the PTB domain of Tensin2. | 9 |
| 23233134 | 2013 | Interaction of DISC1 with the PTB domain of Tensin2. | 9 |
| 22019427 | 2012 | The protein-tyrosine kinase Syk interacts with the C-terminal region of tensin2. | 5 |
Citation
Dessen P
TNS2 (tensin 2)
Atlas Genet Cytogenet Oncol Haematol. 2009-04-01
Online version: http://atlasgeneticsoncology.org/gene/50833/tns2-(tensin-2)
