Identity
HGNC
LOCATION
1p34.2
LOCUSID
ALIAS
JHDM3A,JMJD2,JMJD2A,TDRD14A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9682
MIM: 609764
HGNC: 22978
Ensembl: ENSG00000066135
Variants:
dbSNP: 9682
ClinVar: 9682
TCGA: ENSG00000066135
COSMIC: KDM4A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000066135 | ENST00000372396 | O75164 |
| ENSG00000066135 | ENST00000463151 | A0A2R8YDF7 |
| ENSG00000066135 | ENST00000485249 | A0A2R8Y7L1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37873881 | 2024 | The role of KDM4A-mediated histone methylation on temozolomide resistance in glioma cells through the HUWE1/ROCK2 axis. | 0 |
| 37873881 | 2024 | The role of KDM4A-mediated histone methylation on temozolomide resistance in glioma cells through the HUWE1/ROCK2 axis. | 0 |
| 37165308 | 2023 | JMJD2A participates in cytoskeletal remodeling to regulate castration-resistant prostate cancer docetaxel resistance. | 0 |
| 37553362 | 2023 | Carcinogenesis promotion in oral squamous cell carcinoma: KDM4A complex-mediated gene transcriptional suppression by LEF1. | 1 |
| 37870957 | 2023 | SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A. | 0 |
| 37165308 | 2023 | JMJD2A participates in cytoskeletal remodeling to regulate castration-resistant prostate cancer docetaxel resistance. | 0 |
| 37553362 | 2023 | Carcinogenesis promotion in oral squamous cell carcinoma: KDM4A complex-mediated gene transcriptional suppression by LEF1. | 1 |
| 37870957 | 2023 | SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A. | 0 |
| 35833065 | 2022 | Investigation of the Mechanism of hsa_circ_000 1429 Adsorbed miR-205 to Regulate KDM4A and Promote Breast Cancer Metastasis. | 4 |
| 35914074 | 2022 | SUMO Modification of Histone Demethylase KDM4A in Kaposi's Sarcoma-Associated Herpesvirus-Induced Primary Effusion Lymphoma. | 2 |
| 35833065 | 2022 | Investigation of the Mechanism of hsa_circ_000 1429 Adsorbed miR-205 to Regulate KDM4A and Promote Breast Cancer Metastasis. | 4 |
| 35914074 | 2022 | SUMO Modification of Histone Demethylase KDM4A in Kaposi's Sarcoma-Associated Herpesvirus-Induced Primary Effusion Lymphoma. | 2 |
| 33492339 | 2021 | Mechanistic insights into KDM4A driven genomic instability. | 10 |
| 33599278 | 2021 | Histone demethylase KDM4A overexpression improved the efficiency of corrected human tripronuclear zygote development. | 2 |
| 33689883 | 2021 | KDM4A-mediated histone demethylation of SLC7A11 inhibits cell ferroptosis in osteosarcoma. | 43 |
Citation
Dessen P
KDM4A (lysine demethylase 4A)
Atlas Genet Cytogenet Oncol Haematol. 2009-04-01
Online version: http://atlasgeneticsoncology.org/gene/50835/kdm4a-(lysine-demethylase-4a)
