CD5L (CD5 molecule like)

2009-04-01  

Identity

HGNC
LOCATION
1q23.1
LOCUSID
ALIAS
AIM,API6,CT-2,PRO229,SP-ALPHA,Spalpha,hAIM

Other Information

Locus ID:

NCBI: 922
MIM: 602592
HGNC: 1690
Ensembl: ENSG00000073754

Variants:

dbSNP: 922
ClinVar: 922
TCGA: ENSG00000073754
COSMIC: CD5L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000073754ENST00000368174O43866

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
192047262009Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease.63
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
160300182005A role for human Sp alpha as a pattern recognition receptor.32
191555142009Myeloid-specific expression of Api6/AIM/Sp alpha induces systemic inflammation and adenocarcinoma in the lung.31
267268782016Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice.30
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
186604892008Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.26
242239912013The scavenger protein apoptosis inhibitor of macrophages (AIM) potentiates the antimicrobial response against Mycobacterium tuberculosis by enhancing autophagy.20
260489802015AIM/CD5L: a key protein in the control of immune homeostasis and inflammatory disease.19
257139832015The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses.16

Citation

Dessen P

CD5L (CD5 molecule like)

Atlas Genet Cytogenet Oncol Haematol. 2009-04-01

Online version: http://atlasgeneticsoncology.org/gene/50837/cd5l-(cd5-molecule-like)