MATN2 (matrilin 2)

2009-04-01  

Identity

HGNC
MATN2
LOCATION
8q22.1
LOCUSID
4147
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4147
MIM: 602108
HGNC: 6908
Ensembl: ENSG00000132561

Variants:

dbSNP: 4147
ClinVar: 4147
TCGA: ENSG00000132561
COSMIC: MATN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132561ENST00000254898O00339
ENSG00000132561ENST00000254898A0A140VKH7
ENSG00000132561ENST00000517321H0YBN2
ENSG00000132561ENST00000518154H0YBJ4
ENSG00000132561ENST00000519582H0YBU5
ENSG00000132561ENST00000519585E5RJM4
ENSG00000132561ENST00000520016O00339
ENSG00000132561ENST00000520016A0A140VKH7
ENSG00000132561ENST00000521041H0YBV5
ENSG00000132561ENST00000521689O00339
ENSG00000132561ENST00000521952H0YBD5
ENSG00000132561ENST00000522025O00339
ENSG00000132561ENST00000522135H0YBF2
ENSG00000132561ENST00000522270H0YBM3
ENSG00000132561ENST00000524308O00339

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
197306832009The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.59
198345352009Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.27
164018632006Matrilin-2 expression distinguishes clinically relevant subsets of pilocytic astrocytoma.16
121809072002Matrilin-2 interacts with itself and with other extracellular matrix proteins.12
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
183288062008DeltaNp63/BMP-7-dependent expression of matrilin-2 is involved in keratinocyte migration in response to wounding.10
183861662008Expression of matrilin-2 in liver cirrhosis and hepatocellular carcinoma.8
121649222002Expression of matrilin-2 in human skin.6
118522322002Comparative analysis of the mouse and human genes (Matn2 and MATN2) for matrilin-2, a filament-forming protein widely distributed in extracellular matrices.5

Citation

Dessen P

MATN2 (matrilin 2)

Atlas Genet Cytogenet Oncol Haematol. 2009-04-01

Online version: http://atlasgeneticsoncology.org/gene/50840/matn2-(matrilin-2)