Identity
HGNC
LOCATION
11p11.2
LOCUSID
ALIAS
KAR,SDR12C1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51144
MIM: 609574
HGNC: 18646
Ensembl: ENSG00000149084
Variants:
dbSNP: 51144
ClinVar: 51144
TCGA: ENSG00000149084
COSMIC: HSD17B12
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34762930 | 2022 | Association of genetic polymorphisms with local steroid metabolism in human benign breasts. | 2 |
| 35404482 | 2022 | Genetic variants in CYP2B6 and HSD17B12 associated with risk of squamous cell carcinoma of the head and neck. | 4 |
| 34762930 | 2022 | Association of genetic polymorphisms with local steroid metabolism in human benign breasts. | 2 |
| 35404482 | 2022 | Genetic variants in CYP2B6 and HSD17B12 associated with risk of squamous cell carcinoma of the head and neck. | 4 |
| 31302749 | 2020 | Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration. | 6 |
| 32132633 | 2020 | Very-long-chain fatty acid metabolic capacity of 17-beta-hydroxysteroid dehydrogenase type 12 (HSD17B12) promotes replication of hepatitis C virus and related flaviviruses. | 12 |
| 32340285 | 2020 | An Integrative Phenotype-Genotype Approach Using Phenotypic Characteristics from the UAE National Diabetes Study Identifies HSD17B12 as a Candidate Gene for Obesity and Type 2 Diabetes. | 11 |
| 33118286 | 2020 | Functional genetic variant of HSD17B12 in the fatty acid biosynthesis pathway predicts the outcome of colorectal cancer. | 4 |
| 31302749 | 2020 | Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration. | 6 |
| 32132633 | 2020 | Very-long-chain fatty acid metabolic capacity of 17-beta-hydroxysteroid dehydrogenase type 12 (HSD17B12) promotes replication of hepatitis C virus and related flaviviruses. | 12 |
| 32340285 | 2020 | An Integrative Phenotype-Genotype Approach Using Phenotypic Characteristics from the UAE National Diabetes Study Identifies HSD17B12 as a Candidate Gene for Obesity and Type 2 Diabetes. | 11 |
| 33118286 | 2020 | Functional genetic variant of HSD17B12 in the fatty acid biosynthesis pathway predicts the outcome of colorectal cancer. | 4 |
| 30734280 | 2019 | Genetic variants in ELOVL2 and HSD17B12 predict melanoma-specific survival. | 6 |
| 30734280 | 2019 | Genetic variants in ELOVL2 and HSD17B12 predict melanoma-specific survival. | 6 |
| 29324448 | 2018 | The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer. | 8 |
Citation
Dessen P
HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12)
Atlas Genet Cytogenet Oncol Haematol. 2009-04-01
Online version: http://atlasgeneticsoncology.org/gene/50841/hsd17b12-(hydroxysteroid-17-beta-dehydrogenase-12)
