DDA1 (DET1 and DDB1 associated 1)

2009-04-01  

Identity

HGNC
DDA1
LOCATION
19p13.11
LOCUSID
79016
ALIAS
C19orf58,PCIA1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79016
HGNC: 28360
Ensembl: ENSG00000130311

Variants:

dbSNP: 79016
ClinVar: 79016
TCGA: ENSG00000130311
COSMIC: DDA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130311ENST00000359866Q9BW61
ENSG00000130311ENST00000359866A0A024R7J7
ENSG00000130311ENST00000593466Q9BW61
ENSG00000130311ENST00000593466A0A024R7J7
ENSG00000130311ENST00000596582Q9BW61
ENSG00000130311ENST00000596582A0A024R7J7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
bone marrow

References

Pubmed IDYearTitleCitations
280876992017Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase.6
282111592017DDA1, a novel oncogene, promotes lung cancer progression through regulation of cell cycle.12
291666002017Dopamine Receptor DAMB Signals via Gq to Mediate Forgetting in Drosophila.47
280876992017Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase.6
282111592017DDA1, a novel oncogene, promotes lung cancer progression through regulation of cell cycle.12
291666002017Dopamine Receptor DAMB Signals via Gq to Mediate Forgetting in Drosophila.47
269426992016DDA1 promotes stage IIB-IIC colon cancer progression by activating NFκB/CSN2/GSK-3β signaling.4
269426992016DDA1 promotes stage IIB-IIC colon cancer progression by activating NFκB/CSN2/GSK-3β signaling.4
192951302009An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases.47
192951302009An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases.47
175572372007[Searching for genes interacting with human PCIA1 gene by using the bacterial two-hybrid system].2
175572372007[Searching for genes interacting with human PCIA1 gene by using the bacterial two-hybrid system].2

Citation

Dessen P

DDA1 (DET1 and DDB1 associated 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-04-01

Online version: http://atlasgeneticsoncology.org/gene/50852/dda1-(det1-and-ddb1-associated-1)