Identity
HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
JMJD3,NEDCFSA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23135
MIM: 611577
HGNC: 29012
Ensembl: ENSG00000132510
Variants:
dbSNP: 23135
ClinVar: 23135
TCGA: ENSG00000132510
COSMIC: KDM6B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000132510 | ENST00000254846 | O15054 |
| ENSG00000132510 | ENST00000448097 | O15054 |
| ENSG00000132510 | ENST00000570632 | I3L0Z0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37837219 | 2024 | The ATF4-regulated LncRNA MALAT1 promotes odontoblastic differentiation of human dental pulp stem cells via histone demethylase JMJD3: An in vitro study. | 0 |
| 37917239 | 2024 | Targeting lysine demethylase 6B ameliorates ASXL1 truncation-mediated myeloid malignancies in preclinical models. | 1 |
| 38218880 | 2024 | MicroRNA-93-5p regulates odontogenic differentiation and dentin formation via KDM6B. | 0 |
| 38245781 | 2024 | YAP represses intestinal inflammation through epigenetic silencing of JMJD3. | 0 |
| 37837219 | 2024 | The ATF4-regulated LncRNA MALAT1 promotes odontoblastic differentiation of human dental pulp stem cells via histone demethylase JMJD3: An in vitro study. | 0 |
| 37917239 | 2024 | Targeting lysine demethylase 6B ameliorates ASXL1 truncation-mediated myeloid malignancies in preclinical models. | 1 |
| 38218880 | 2024 | MicroRNA-93-5p regulates odontogenic differentiation and dentin formation via KDM6B. | 0 |
| 38245781 | 2024 | YAP represses intestinal inflammation through epigenetic silencing of JMJD3. | 0 |
| 36427698 | 2023 | KDM6B regulates M2 polarization of macrophages by modulating the stability of nuclear β-catenin. | 1 |
| 36791533 | 2023 | Aberrant expression of JMJD3 in SLE promotes B-cell differentiation. | 1 |
| 36797416 | 2023 | KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress. | 4 |
| 37286519 | 2023 | JMJD3 is Involved in Intracranial Aneurysm Development by Regulating DLX2 Expression through H3K27me3 Modification. | 0 |
| 37478314 | 2023 | NOTCH4 potentiates the IL-13 induced genetic program in M2 alternative macrophages through the AP1 and IRF4-JMJD3 axis. | 2 |
| 37574036 | 2023 | E2F1-driven histone demethylase KDM6B enhances thyroid malignancy via manipulating TFEB-dependent autophagy axis. | 0 |
| 37653141 | 2023 | Myeloid-specific KDM6B inhibition sensitizes glioblastoma to PD1 blockade. | 7 |
Citation
Dessen P
KDM6B (lysine demethylase 6B)
Atlas Genet Cytogenet Oncol Haematol. 2009-05-01
Online version: http://atlasgeneticsoncology.org/gene/50868/kdm6b-(lysine-demethylase-6b)
