MIIP (migration and invasion inhibitory protein)

2009-05-01 Affiliation

Identity

HGNC

MIIP

LOCATION

1p36.22

LOCUSID

60672

ALIAS

IIP45

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 60672
MIM: 608772
HGNC: 25715
Ensembl: ENSG00000116691

Variants:

dbSNP: 60672
ClinVar: 60672
TCGA: ENSG00000116691
COSMIC: MIIP

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000116691	ENST00000235332	Q5JXC2

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
34931765	2021	MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis.	3
34931765	2021	MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis.	3
32196585	2020	MIIP inhibits malignant progression of hepatocellular carcinoma through regulating AKT.	2
32196585	2020	MIIP inhibits malignant progression of hepatocellular carcinoma through regulating AKT.	2
31078343	2019	Upregulation of MIIP regulates human breast cancer proliferation, invasion and migration by mediated by IGFBP2.	7
31092266	2019	MIIP inhibits the growth of prostate cancer via interaction with PP1α and negative modulation of AKT signaling.	9
31078343	2019	Upregulation of MIIP regulates human breast cancer proliferation, invasion and migration by mediated by IGFBP2.	7
31092266	2019	MIIP inhibits the growth of prostate cancer via interaction with PP1α and negative modulation of AKT signaling.	9
29343850	2018	MiRNA-646-mediated reciprocal repression between HIF-1α and MIIP contributes to tumorigenesis of pancreatic cancer.	27
29343850	2018	MiRNA-646-mediated reciprocal repression between HIF-1α and MIIP contributes to tumorigenesis of pancreatic cancer.	27
27741356	2017	MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer.	11
29038521	2017	PKCε phosphorylates MIIP and promotes colorectal cancer metastasis through inhibition of RelA deacetylation.	21
27741356	2017	MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer.	11
29038521	2017	PKCε phosphorylates MIIP and promotes colorectal cancer metastasis through inhibition of RelA deacetylation.	21
26825982	2016	MIIP expression predicts outcomes of surgically resected esophageal squamous cell carcinomas.	4

Citation

Dessen P

MIIP (migration and invasion inhibitory protein)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50899/miip-(migration-and-invasion-inhibitory-protein)