Identity
HGNC
LOCATION
20q13.13
LOCUSID
ALIAS
NHE-8,NHE8
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23315
MIM: 612730
HGNC: 20728
Ensembl: ENSG00000197818
Variants:
dbSNP: 23315
ClinVar: 23315
TCGA: ENSG00000197818
COSMIC: SLC9A8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000197818 | ENST00000361573 | Q9Y2E8 |
| ENSG00000197818 | ENST00000417961 | Q9Y2E8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36583805 | 2023 | Downregulation of SLC9A8 Promotes Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer Cells via the IL6-JAK1/STAT3 Signaling Pathway. | 2 |
| 36583805 | 2023 | Downregulation of SLC9A8 Promotes Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer Cells via the IL6-JAK1/STAT3 Signaling Pathway. | 2 |
| 34288721 | 2021 | Functional characterization of the sodium/hydrogen exchanger 8 and its role in proliferation of colonic epithelial cells. | 6 |
| 34288721 | 2021 | Functional characterization of the sodium/hydrogen exchanger 8 and its role in proliferation of colonic epithelial cells. | 6 |
| 28476888 | 2017 | Loss of the Na(+)/H(+) exchanger NHE8 causes male infertility in mice by disrupting acrosome formation. | 22 |
| 28476888 | 2017 | Loss of the Na(+)/H(+) exchanger NHE8 causes male infertility in mice by disrupting acrosome formation. | 22 |
| 26564720 | 2016 | Intestinal NHE8 is highly expressed in goblet cells and its expression is subject to TNF-α regulation. | 8 |
| 26564720 | 2016 | Intestinal NHE8 is highly expressed in goblet cells and its expression is subject to TNF-α regulation. | 8 |
| 21171650 | 2011 | Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions. | 45 |
| 21666503 | 2011 | Nucleotide sequence of the Na+/H+ exchanger-8 in patients with congenital sodium diarrhea. | 6 |
| 21171650 | 2011 | Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions. | 45 |
| 21666503 | 2011 | Nucleotide sequence of the Na+/H+ exchanger-8 in patients with congenital sodium diarrhea. | 6 |
| 20375273 | 2010 | Epidermal growth factor inhibits intestinal NHE8 expression via reducing its basal transcription. | 14 |
| 20719963 | 2010 | The sodium/proton exchanger NHE8 regulates late endosomal morphology and function. | 26 |
| 20375273 | 2010 | Epidermal growth factor inhibits intestinal NHE8 expression via reducing its basal transcription. | 14 |
Citation
Dessen P
SLC9A8 (solute carrier family 9 member A8)
Atlas Genet Cytogenet Oncol Haematol. 2009-05-01
Online version: http://atlasgeneticsoncology.org/gene/50908/slc9a8-(solute-carrier-family-9-member-a8)
