Identity
HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
DF5L,DFNA5L,FKSG10,GSDMDC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79792
MIM: 617042
HGNC: 25697
Ensembl: ENSG00000104518
Variants:
dbSNP: 79792
ClinVar: 79792
TCGA: ENSG00000104518
COSMIC: GSDMD
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37914099 | 2024 | Gasdermin D activation in oligodendrocytes and microglia drives inflammatory demyelination in progressive multiple sclerosis. | 0 |
| 37931722 | 2024 | CHMP4B and VSP4A reverse GSDMD-mediated pyroptosis by cell membrane remodeling in endometrial carcinoma. | 2 |
| 37962578 | 2024 | O-GlcNAc modification of GSDMD attenuates LPS-induced endothelial cells pyroptosis. | 0 |
| 38242759 | 2024 | Gasdermin D triggers cardiolipin-driven mitochondrial damage and pyroptosis. | 0 |
| 38250727 | 2024 | GSDMD suppresses keratinocyte differentiation by inhibiting FLG expression and attenuating KCTD6-mediated HDAC1 degradation in atopic dermatitis. | 0 |
| 38295720 | 2024 | Gasdermin D regulates soluble fms-like tyrosine kinase 1 release in macrophages. | 0 |
| 38429762 | 2024 | TR4 worsen urosepsis by regulating GSDMD. | 0 |
| 38530158 | 2024 | The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. | 6 |
| 38548966 | 2024 | Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma. | 0 |
| 38599239 | 2024 | ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. | 2 |
| 38617450 | 2024 | Silent information regulator sirtuin 1 ameliorates acute liver failure via the p53/glutathione peroxidase 4/gasdermin D axis. | 2 |
| 38831451 | 2024 | Gasdermin D deficiency aborts myeloid calcium influx to drive granulopoiesis in lupus nephritis. | 0 |
| 38993566 | 2024 | P2X7R Modulates NEK7-NLRP3 Interaction to Exacerbate Experimental Autoimmune Prostatitis via GSDMD-mediated Prostate Epithelial Cell Pyroptosis. | 0 |
| 37914099 | 2024 | Gasdermin D activation in oligodendrocytes and microglia drives inflammatory demyelination in progressive multiple sclerosis. | 0 |
| 37931722 | 2024 | CHMP4B and VSP4A reverse GSDMD-mediated pyroptosis by cell membrane remodeling in endometrial carcinoma. | 2 |
Citation
Dessen P
GSDMD (gasdermin D)
Atlas Genet Cytogenet Oncol Haematol. 2009-05-01
Online version: http://atlasgeneticsoncology.org/gene/50915/gsdmd-(gasdermin-d)
