Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2556
MIM: 305660
HGNC: 4077
Ensembl: ENSG00000011677
Variants:
dbSNP: 2556
ClinVar: 2556
TCGA: ENSG00000011677
COSMIC: GABRA3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000011677 | ENST00000370314 | P34903 |
| ENSG00000011677 | ENST00000535043 | P34903 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31593956 | 2019 | Epigenetic Coactivation of MAGEA6 and CT-GABRA3 Defines Orientation of a Segmental Duplication in the Human X Chromosome. | 4 |
| 31610743 | 2019 | Anterograde trafficking signals in GABA(A) subunits are required for functional expression. | 0 |
| 31841197 | 2019 | MiR-92b inhibited cells EMT by targeting Gabra3 and predicted prognosis of triple negative breast cancer patients. | 8 |
| 31593956 | 2019 | Epigenetic Coactivation of MAGEA6 and CT-GABRA3 Defines Orientation of a Segmental Duplication in the Human X Chromosome. | 4 |
| 31610743 | 2019 | Anterograde trafficking signals in GABA(A) subunits are required for functional expression. | 0 |
| 31841197 | 2019 | MiR-92b inhibited cells EMT by targeting Gabra3 and predicted prognosis of triple negative breast cancer patients. | 8 |
| 29023704 | 2018 | GABA(A) receptor subunits in the human amygdala and hippocampus: Immunohistochemical distribution of 7 subunits. | 19 |
| 29023704 | 2018 | GABA(A) receptor subunits in the human amygdala and hippocampus: Immunohistochemical distribution of 7 subunits. | 19 |
| 29053855 | 2017 | Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features. | 20 |
| 29053855 | 2017 | Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features. | 20 |
| 26518133 | 2016 | The α1, α2, α3, and γ2 subunits of GABAA receptors show characteristic spatial and temporal expression patterns in rhombencephalic structures during normal human brain development. | 10 |
| 26869349 | 2016 | The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis. | 98 |
| 27081042 | 2016 | GABRA3 promotes lymphatic metastasis in lung adenocarcinoma by mediating upregulation of matrix metalloproteinases. | 12 |
| 27412533 | 2016 | Identification of Positive Allosteric Modulators of Glycine Receptors from a High-Throughput Screen Using a Fluorescent Membrane Potential Assay. | 4 |
| 26518133 | 2016 | The α1, α2, α3, and γ2 subunits of GABAA receptors show characteristic spatial and temporal expression patterns in rhombencephalic structures during normal human brain development. | 10 |
Citation
Dessen P
GABRA3 (gamma-aminobutyric acid type A receptor subunit alpha3)
Atlas Genet Cytogenet Oncol Haematol. 2009-05-01
Online version: http://atlasgeneticsoncology.org/gene/50916/gabra3
