Identity
HGNC
LOCATION
11q13.4
LOCUSID
ALIAS
ABDH19,PME-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51400
MIM: 611117
HGNC: 30178
Ensembl: ENSG00000214517
Variants:
dbSNP: 51400
ClinVar: 51400
TCGA: ENSG00000214517
COSMIC: PPME1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000214517 | ENST00000328257 | Q9Y570 |
| ENSG00000214517 | ENST00000328257 | A0A140VK39 |
| ENSG00000214517 | ENST00000398427 | Q9Y570 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38588804 | 2024 | The luciferase-based in vivo protein-protein interaction assay revealed that CHK1 promotes PP2A and PME-1 interaction. | 0 |
| 38588804 | 2024 | The luciferase-based in vivo protein-protein interaction assay revealed that CHK1 promotes PP2A and PME-1 interaction. | 0 |
| 36461911 | 2023 | PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers. | 4 |
| 36461911 | 2023 | PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers. | 4 |
| 32071079 | 2020 | Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1. | 34 |
| 32351291 | 2020 | DNAH17-AS1 promotes pancreatic carcinoma by increasing PPME1 expression via inhibition of miR-432-5p. | 13 |
| 32071079 | 2020 | Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1. | 34 |
| 32351291 | 2020 | DNAH17-AS1 promotes pancreatic carcinoma by increasing PPME1 expression via inhibition of miR-432-5p. | 13 |
| 31714894 | 2019 | Glycogen synthase kinase-3β suppresses the expression of protein phosphatase methylesterase-1 through β-catenin. | 3 |
| 31714894 | 2019 | Glycogen synthase kinase-3β suppresses the expression of protein phosphatase methylesterase-1 through β-catenin. | 3 |
| 29577269 | 2018 | PME-1 is regulated by USP36 in ERK and Akt signaling pathways. | 6 |
| 30340029 | 2018 | Hydrogen peroxide redistributes the localization of protein phosphatase methylesterase 1. | 2 |
| 29577269 | 2018 | PME-1 is regulated by USP36 in ERK and Akt signaling pathways. | 6 |
| 30340029 | 2018 | Hydrogen peroxide redistributes the localization of protein phosphatase methylesterase 1. | 2 |
| 27810903 | 2017 | NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability. | 41 |
Citation
Dessen P
PPME1 (protein phosphatase methylesterase 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-06-01
Online version: http://atlasgeneticsoncology.org/gene/50942/ppme1-(protein-phosphatase-methylesterase-1)
