HAX1 (HCLS1 associated protein X-1)

2009-06-01  

Identity

HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
HCLSBP1,HS1BP1,SCN3

Other Information

Locus ID:

NCBI: 10456
MIM: 605998
HGNC: 16915
Ensembl: ENSG00000143575

Variants:

dbSNP: 10456
ClinVar: 10456
TCGA: ENSG00000143575
COSMIC: HAX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143575ENST00000328703O00165
ENSG00000143575ENST00000328703A0A0S2Z591
ENSG00000143575ENST00000435087Q5VYD6
ENSG00000143575ENST00000447768O00165
ENSG00000143575ENST00000457918O00165
ENSG00000143575ENST00000457918A0A0S2Z565
ENSG00000143575ENST00000483970O00165
ENSG00000143575ENST00000532105E9PIQ7

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
377427222024HAX1 is a novel binding partner of Che-1/AATF. Implications in oxidative stress cell response.0
385146062024The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression.0
387694382024Energy stress promotes P-bodies formation via lysine-63-linked polyubiquitination of HAX1.0
377427222024HAX1 is a novel binding partner of Che-1/AATF. Implications in oxidative stress cell response.0
385146062024The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression.0
387694382024Energy stress promotes P-bodies formation via lysine-63-linked polyubiquitination of HAX1.0
371936392023HAX1-related congenital neutropenia: Long-term observation in paediatric and adult patients enrolled in the European branch of the Severe Chronic Neutropenia International Registry (SCNIR).0
374889672023NOD1 cooperates with HAX-1 to promote cell migration in a RIPK2- and NF-ĸB-independent manner.1
371936392023HAX1-related congenital neutropenia: Long-term observation in paediatric and adult patients enrolled in the European branch of the Severe Chronic Neutropenia International Registry (SCNIR).0
374889672023NOD1 cooperates with HAX-1 to promote cell migration in a RIPK2- and NF-ĸB-independent manner.1
335600822022A Novel Intronic Mutation Reduces HAX1 Level and is Associated With Severe Congenital Neutropenia.0
350158502022Hsa-miR223-3p circulating level is upregulated in Friedreich's ataxia and inversely associated with HCLS1 associated protein X-1, HAX-1.3
353022982022Effect of different expression patterns of HAX-1 on the proliferation and apoptosis of human astrocyte.0
354990782022HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation.9
355244422022Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation.15

Citation

Dessen P

HAX1 (HCLS1 associated protein X-1)

Atlas Genet Cytogenet Oncol Haematol. 2009-06-01

Online version: http://atlasgeneticsoncology.org/gene/50953