Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3954
MIM: 604407
HGNC: 6556
Ensembl: ENSG00000168924
Variants:
dbSNP: 3954
ClinVar: 3954
TCGA: ENSG00000168924
COSMIC: LETM1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168924 | ENST00000302787 | O95202 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36056285 | 2023 | Circ_0061140 Contributes to Ovarian Cancer Progression by Targeting miR-761/LETM1 Signaling. | 4 |
| 36056285 | 2023 | Circ_0061140 Contributes to Ovarian Cancer Progression by Targeting miR-761/LETM1 Signaling. | 4 |
| 33314691 | 2021 | Suppression of LETM1 inhibits the proliferation and stemness of colorectal cancer cells through reactive oxygen species-induced autophagy. | 10 |
| 33576522 | 2021 | The leucine zipper EF-hand containing transmembrane protein-1 EF-hand is a tripartite calcium, temperature, and pH sensor. | 3 |
| 34605738 | 2021 | LETM1 (leucine zipper-EF-hand-containing transmembrane protein 1) silence reduces the proliferation, invasion, migration and angiogenesis in esophageal squamous cell carcinoma via KIF14 (kinesin family member 14). | 7 |
| 33314691 | 2021 | Suppression of LETM1 inhibits the proliferation and stemness of colorectal cancer cells through reactive oxygen species-induced autophagy. | 10 |
| 33576522 | 2021 | The leucine zipper EF-hand containing transmembrane protein-1 EF-hand is a tripartite calcium, temperature, and pH sensor. | 3 |
| 34605738 | 2021 | LETM1 (leucine zipper-EF-hand-containing transmembrane protein 1) silence reduces the proliferation, invasion, migration and angiogenesis in esophageal squamous cell carcinoma via KIF14 (kinesin family member 14). | 7 |
| 31705880 | 2020 | LETM1 is a potential biomarker that predicts poor prognosis in gastric adenocarcinoma. | 8 |
| 32139798 | 2020 | The mitochondrial inner membrane protein LETM1 modulates cristae organization through its LETM domain. | 23 |
| 32633345 | 2020 | MiR-613 blocked the progression of cervical cancer by targeting LETM1. | 6 |
| 32705272 | 2020 | Whole‑exome sequencing identifies a novel mutation of SLC20A2 (c.C1849T) as a possible cause of hereditary multiple exostoses in a Chinese family. | 1 |
| 31705880 | 2020 | LETM1 is a potential biomarker that predicts poor prognosis in gastric adenocarcinoma. | 8 |
| 32139798 | 2020 | The mitochondrial inner membrane protein LETM1 modulates cristae organization through its LETM domain. | 23 |
| 32633345 | 2020 | MiR-613 blocked the progression of cervical cancer by targeting LETM1. | 6 |
Citation
Dessen P
LETM1 (leucine zipper and EF-hand containing transmembrane protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-06-01
Online version: http://atlasgeneticsoncology.org/gene/50978/letm1-(leucine-zipper-and-ef-hand-containing-transmembrane-protein-1)
