KRT23 (keratin 23)

2009-06-01  

Identity

HGNC
KRT23
LOCATION
17q21.2
LOCUSID
25984
ALIAS
CK23,HAIK1,K23
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 25984
MIM: 606194
HGNC: 6438
Ensembl: ENSG00000108244

Variants:

dbSNP: 25984
ClinVar: 25984
TCGA: ENSG00000108244
COSMIC: KRT23

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108244ENST00000209718Q9C075
ENSG00000108244ENST00000209718A0A024R1X9
ENSG00000108244ENST00000436344Q9C075
ENSG00000108244ENST00000462312Q9UFN7
ENSG00000108244ENST00000485751K7EPI0
ENSG00000108244ENST00000494691Q9UFN7
ENSG00000108244ENST00000584517J3QR55

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
KeratinizationREACTOMER-HSA-6805567

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
332047162020The Overexpression of Keratin 23 Promotes Migration of Ovarian Cancer via Epithelial-Mesenchymal Transition.12
332047162020The Overexpression of Keratin 23 Promotes Migration of Ovarian Cancer via Epithelial-Mesenchymal Transition.12
306977912019Keratin 23 Is a Peroxisome Proliferator-Activated Receptor Alpha-Dependent, MYC-Amplified Oncogene That Promotes Hepatocyte Proliferation.23
312167132019Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver.2
306977912019Keratin 23 Is a Peroxisome Proliferator-Activated Receptor Alpha-Dependent, MYC-Amplified Oncogene That Promotes Hepatocyte Proliferation.23
312167132019Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver.2
277521442016LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis.18
277521442016LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis.18
236820782013Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions.17
240399932013Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells.26
236820782013Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions.17
240399932013Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells.26
214924762011Keratin 23, a novel DPC4/Smad4 target gene which binds 14-3-3ε.18
214924762011Keratin 23, a novel DPC4/Smad4 target gene which binds 14-3-3ε.18
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.30

Citation

Dessen P

KRT23 (keratin 23)

Atlas Genet Cytogenet Oncol Haematol. 2009-06-01

Online version: http://atlasgeneticsoncology.org/gene/50983/krt23-(keratin-23)