Identity
HGNC
LOCATION
Xp11.3
LOCUSID
ALIAS
KABUK2,UTX,bA386N14.2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7403
MIM: 300128
HGNC: 12637
Ensembl: ENSG00000147050
Variants:
dbSNP: 7403
ClinVar: 7403
TCGA: ENSG00000147050
COSMIC: KDM6A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38171564 | 2024 | [Clinical characteristics and genetic counseling for a three-generation Chinese pedigree with recurrent fetal Kabuki syndrome due to variant of KDM6A gene]. | 0 |
| 38171564 | 2024 | [Clinical characteristics and genetic counseling for a three-generation Chinese pedigree with recurrent fetal Kabuki syndrome due to variant of KDM6A gene]. | 0 |
| 36215227 | 2023 | Homeobox A3 and KDM6A cooperate in transcriptional control of aerobic glycolysis and glioblastoma progression. | 3 |
| 36638328 | 2023 | KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer. | 8 |
| 36720973 | 2023 | KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition. | 3 |
| 36753963 | 2023 | The role of lysine-specific demethylase 6A (KDM6A) in tumorigenesis and its therapeutic potentials in cancer therapy. | 2 |
| 36877334 | 2023 | Dual-Regulated Mechanism of EZH2 and KDM6A on SALL4 Modulates Tumor Progression via Wnt/β-Catenin Pathway in Gastric Cancer. | 2 |
| 36928413 | 2023 | The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences. | 20 |
| 36941815 | 2023 | Lysine-specific Demethylase 6A Upregulates Cadherin-1 and Accelerates Gastric Cancer Growth. | 0 |
| 36980177 | 2023 | Differential Occupancy and Regulatory Interactions of KDM6A in Bladder Cell Lines. | 1 |
| 37060821 | 2023 | Downregulated KDM6A mediates gastric carcinogenesis via Wnt/β-catenin signaling pathway mediated epithelial-to-mesenchymal transition. | 0 |
| 37300822 | 2023 | Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types. | 1 |
| 37315471 | 2023 | Downregulation of lncRNA XIST may promote Th17 differentiation through KDM6A-TSAd pathway in neuromyelitis optica spectrum disorders. | 3 |
| 37410700 | 2023 | The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression. | 0 |
| 37657612 | 2023 | The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system. | 1 |
Citation
Dessen P
KDM6A (lysine demethylase 6A)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/50993
