Identity
HGNC
LOCATION
3q22.1
LOCUSID
ALIAS
CC-CKR-11,CCBP2,CCR-11,CCR10,CCR11,CCRL1,CCX
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51554
MIM: 606065
HGNC: 1611
Ensembl: ENSG00000129048
Variants:
dbSNP: 51554
ClinVar: 51554
TCGA: ENSG00000129048
COSMIC: ACKR4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000129048 | ENST00000249887 | Q9NPB9 |
| ENSG00000129048 | ENST00000509820 | H0Y9Z2 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38597217 | 2024 | Atypical chemokine receptor 4 (ACKR4/CCX-CKR): A comprehensive exploration across physiological and pathological landscapes in contemporary research. | 0 |
| 38597217 | 2024 | Atypical chemokine receptor 4 (ACKR4/CCX-CKR): A comprehensive exploration across physiological and pathological landscapes in contemporary research. | 0 |
| 37449198 | 2023 | Identification of ACKR4 as an immune checkpoint in pulmonary arterial hypertension. | 1 |
| 37449198 | 2023 | Identification of ACKR4 as an immune checkpoint in pulmonary arterial hypertension. | 1 |
| 35108538 | 2022 | Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics. | 7 |
| 35108538 | 2022 | Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics. | 7 |
| 32480426 | 2021 | Systematic reassessment of chemokine-receptor pairings confirms CCL20 but not CXCL13 and extends the spectrum of ACKR4 agonists to CCL22. | 6 |
| 34102193 | 2021 | The relation between ACKR4 and CCR7 genes expression and breast cancer metastasis. | 6 |
| 32480426 | 2021 | Systematic reassessment of chemokine-receptor pairings confirms CCL20 but not CXCL13 and extends the spectrum of ACKR4 agonists to CCL22. | 6 |
| 34102193 | 2021 | The relation between ACKR4 and CCR7 genes expression and breast cancer metastasis. | 6 |
| 32391018 | 2020 | ACKR4 Recruits GRK3 Prior to β-Arrestins but Can Scavenge Chemokines in the Absence of β-Arrestins. | 27 |
| 32533638 | 2020 | CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4. | 14 |
| 33374792 | 2020 | Biphasic Expression of Atypical Chemokine Receptor (ACKR) 2 and ACKR4 in Colorectal Neoplasms in Association with Histopathological Findings. | 6 |
| 32391018 | 2020 | ACKR4 Recruits GRK3 Prior to β-Arrestins but Can Scavenge Chemokines in the Absence of β-Arrestins. | 27 |
| 32533638 | 2020 | CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4. | 14 |
Citation
Dessen P
ACKR4 (atypical chemokine receptor 4)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51003/ackr4-(atypical-chemokine-receptor-4)
