RWDD3 (RWD domain containing 3)

2009-08-01  

Identity

HGNC
LOCATION
1p21.3
LOCUSID
ALIAS
RSUME
FUSION GENES

Other Information

Locus ID:

NCBI: 25950
MIM: 615875
HGNC: 21393
Ensembl: ENSG00000122481

Variants:

dbSNP: 25950
ClinVar: 25950
TCGA: ENSG00000122481
COSMIC: RWDD3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122481ENST00000263893Q9Y3V2
ENSG00000122481ENST00000370202Q9Y3V2

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
SUMOylationREACTOMER-HSA-2990846
Processing and activation of SUMOREACTOMER-HSA-3215018
SUMO is transferred from E1 to E2 (UBE2I, UBC9)REACTOMER-HSA-3065678

References

Pubmed IDYearTitleCitations
355280202022Impact of RSUME Actions on Biomolecular Modifications in Physio-Pathological Processes.1
355280202022Impact of RSUME Actions on Biomolecular Modifications in Physio-Pathological Processes.1
308907012019von Hippel-Lindau mutants in renal cell carcinoma are regulated by increased expression of RSUME.12
308907012019von Hippel-Lindau mutants in renal cell carcinoma are regulated by increased expression of RSUME.12
296226892018Protein stabilization by RSUME accounts for PTTG pituitary tumor abundance and oncogenicity.4
296226892018Protein stabilization by RSUME accounts for PTTG pituitary tumor abundance and oncogenicity.4
279897712017Relationship between RSUME and HIF-1α/VEGF-A with invasion of pituitary adenoma.18
279897712017Relationship between RSUME and HIF-1α/VEGF-A with invasion of pituitary adenoma.18
275069442016RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors.9
275069442016RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors.9
255005452015RSUME inhibits VHL and regulates its tumor suppressor function.14
255495362015RWDD3 and TECTA variants not linked to paclitaxel induced peripheral neuropathy in North American trial Alliance N08C1.6
262978262015Role of RSUME in inflammation and cancer.9
255005452015RSUME inhibits VHL and regulates its tumor suppressor function.14
255495362015RWDD3 and TECTA variants not linked to paclitaxel induced peripheral neuropathy in North American trial Alliance N08C1.6

Citation

Dessen P

RWDD3 (RWD domain containing 3)

Atlas Genet Cytogenet Oncol Haematol. 2009-08-01

Online version: http://atlasgeneticsoncology.org/gene/51010/rwdd3-(rwd-domain-containing-3)