Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55200
MIM: 611743
HGNC: 25562
Ensembl: ENSG00000008323
Variants:
dbSNP: 55200
ClinVar: 55200
TCGA: ENSG00000008323
COSMIC: PLEKHG6
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31988071 | 2020 | Genetic Predisposition to Colon and Rectal Adenocarcinoma Is Mediated by a Super-enhancer Polymorphism Coactivating CD9 and PLEKHG6. | 5 |
| 31988071 | 2020 | Genetic Predisposition to Colon and Rectal Adenocarcinoma Is Mediated by a Super-enhancer Polymorphism Coactivating CD9 and PLEKHG6. | 5 |
| 29321250 | 2018 | Myosin II-interacting guanine nucleotide exchange factor promotes bleb retraction via stimulating cortex reassembly at the bleb membrane. | 10 |
| 30517861 | 2018 | A Primate-Specific Isoform of PLEKHG6 Regulates Neurogenesis and Neuronal Migration. | 27 |
| 29321250 | 2018 | Myosin II-interacting guanine nucleotide exchange factor promotes bleb retraction via stimulating cortex reassembly at the bleb membrane. | 10 |
| 30517861 | 2018 | A Primate-Specific Isoform of PLEKHG6 Regulates Neurogenesis and Neuronal Migration. | 27 |
| 24482237 | 2014 | Phosphorylation of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) at threonine 544 by aurora B kinase promotes the binding of polo-like kinase 1 to MyoGEF. | 5 |
| 25336641 | 2014 | Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions. | 2 |
| 24482237 | 2014 | Phosphorylation of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) at threonine 544 by aurora B kinase promotes the binding of polo-like kinase 1 to MyoGEF. | 5 |
| 25336641 | 2014 | Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions. | 2 |
| 20634288 | 2010 | GIPC1 interacts with MyoGEF and promotes MDA-MB-231 breast cancer cell invasion. | 13 |
| 20634288 | 2010 | GIPC1 interacts with MyoGEF and promotes MDA-MB-231 breast cancer cell invasion. | 13 |
| 19421144 | 2009 | Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC. | 34 |
| 19421144 | 2009 | Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC. | 34 |
| 18694934 | 2008 | Phosphorylation of MyoGEF on Thr-574 by Plk1 promotes MyoGEF localization to the central spindle. | 19 |
Citation
Dessen P
PLEKHG6 (pleckstrin homology and RhoGEF domain containing G6)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51012/plekhg6-(pleckstrin-homology-and-rhogef-domain-containing-g6)
