Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2997
MIM: 138570
HGNC: 4706
Ensembl: ENSG00000104812
Variants:
dbSNP: 2997
ClinVar: 2997
TCGA: ENSG00000104812
COSMIC: GYS1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000104812 | ENST00000263276 | P13807 |
| ENSG00000104812 | ENST00000323798 | P13807 |
| ENSG00000104812 | ENST00000594220 | M0QYU1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35793618 | 2022 | The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex. | 7 |
| 35793618 | 2022 | The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex. | 7 |
| 33219378 | 2021 | Pulmonary glycogen deficiency as a new potential cause of respiratory distress syndrome. | 2 |
| 33219378 | 2021 | Pulmonary glycogen deficiency as a new potential cause of respiratory distress syndrome. | 2 |
| 28596236 | 2017 | Acute Hypoglycemia in Healthy Humans Impairs Insulin-Stimulated Glucose Uptake and Glycogen Synthase in Skeletal Muscle: A Randomized Clinical Study. | 3 |
| 28596236 | 2017 | Acute Hypoglycemia in Healthy Humans Impairs Insulin-Stimulated Glucose Uptake and Glycogen Synthase in Skeletal Muscle: A Randomized Clinical Study. | 3 |
| 25371328 | 2015 | Over-expression of muscle glycogen synthase in human diabetic nephropathy. | 7 |
| 25487600 | 2015 | Overexpression of GYS1, MIF, and MYC is associated with adverse outcome and poor response to azacitidine in myelodysplastic syndromes and acute myeloid leukemia. | 15 |
| 25703587 | 2015 | Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells. | 29 |
| 25371328 | 2015 | Over-expression of muscle glycogen synthase in human diabetic nephropathy. | 7 |
| 25487600 | 2015 | Overexpression of GYS1, MIF, and MYC is associated with adverse outcome and poor response to azacitidine in myelodysplastic syndromes and acute myeloid leukemia. | 15 |
| 25703587 | 2015 | Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells. | 29 |
| 23134486 | 2013 | Regulation of glycogen synthase from mammalian skeletal muscle--a unifying view of allosteric and covalent regulation. | 17 |
| 23321478 | 2013 | Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH₂-terminal (sites 2 + 2a) phosphorylation. | 7 |
| 23134486 | 2013 | Regulation of glycogen synthase from mammalian skeletal muscle--a unifying view of allosteric and covalent regulation. | 17 |
Citation
Dessen P
GYS1 (glycogen synthase 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51017/gys1-(glycogen-synthase-1)
