Identity
HGNC
LOCATION
2q24.2
LOCUSID
ALIAS
CLEC13C,PLA2-R,PLA2G1R,PLA2IR,PLA2R
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22925
MIM: 604939
HGNC: 9042
Ensembl: ENSG00000153246
Variants:
dbSNP: 22925
ClinVar: 22925
TCGA: ENSG00000153246
COSMIC: PLA2R1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000153246 | ENST00000283243 | Q13018 |
| ENSG00000153246 | ENST00000392771 | Q13018 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38454495 | 2024 | Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth. | 0 |
| 38897568 | 2024 | Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17. | 0 |
| 38454495 | 2024 | Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth. | 0 |
| 38897568 | 2024 | Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17. | 0 |
| 37302862 | 2023 | [Mechanism of podocyte pyroptosis aggravated by up-regulation of phospholipase A(2) receptor by hepatitis B virus X protein]. | 0 |
| 37510247 | 2023 | The Role of PLA2R in Primary Membranous Nephropathy: Do We Still Need a Kidney Biopsy? | 2 |
| 37302862 | 2023 | [Mechanism of podocyte pyroptosis aggravated by up-regulation of phospholipase A(2) receptor by hepatitis B virus X protein]. | 0 |
| 37510247 | 2023 | The Role of PLA2R in Primary Membranous Nephropathy: Do We Still Need a Kidney Biopsy? | 2 |
| 35272568 | 2022 | Association of serum mannose-binding lectin, anti-phospholipase A2 receptor antibody and renal outcomes in idiopathic membranous nephropathy and atypical membranous nephropathy: a single center retrospective cohort study. | 3 |
| 35670653 | 2022 | Comprehensively characterizing cellular changes and the expression of THSD7A and PLA2R1 under multiple in vitro models of podocyte injury. | 0 |
| 35272568 | 2022 | Association of serum mannose-binding lectin, anti-phospholipase A2 receptor antibody and renal outcomes in idiopathic membranous nephropathy and atypical membranous nephropathy: a single center retrospective cohort study. | 3 |
| 35670653 | 2022 | Comprehensively characterizing cellular changes and the expression of THSD7A and PLA2R1 under multiple in vitro models of podocyte injury. | 0 |
| 32524521 | 2021 | Identical twins with idiopathic membranous nephropathy. | 2 |
| 32712166 | 2021 | Fumarate modulates phospholipase A2 receptor autoimmunity-induced podocyte injury in membranous nephropathy. | 10 |
| 33184968 | 2021 | sPLA2-IB and PLA2R mediate insufficient autophagy and contribute to podocyte injury in idiopathic membranous nephropathy by activation of the p38MAPK/mTOR/ULK1(ser757) signaling pathway. | 12 |
Citation
Dessen P
PLA2R1 (phospholipase A2 receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51021/pla2r1-(phospholipase-a2-receptor-1)
