Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 345
MIM: 107720
HGNC: 610
Ensembl: ENSG00000110245
Variants:
dbSNP: 345
ClinVar: 345
TCGA: ENSG00000110245
COSMIC: APOC3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164742099 | MTTP | Gene | Pathway | associated | |||
| PA444528 | Hyperlipidemias | Disease | ClinicalAnnotation | associated | PD | 15809899 | |
| PA447230 | HIV Infections | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 15809899 | |
| PA451260 | ritonavir | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 15809899 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37972731 | 2024 | Apolipoprotein C3: form begets function. | 2 |
| 38039351 | 2024 | Exploring apolipoprotein C-III: pathophysiological and pharmacological relevance. | 1 |
| 38232538 | 2024 | Apolipoprotein C3 (ApoC3) facilitates NLRP3 mediated pyroptosis of macrophages through mitochondrial damage by accelerating of the interaction between SCIMP and SYK pathway in acute lung injury. | 0 |
| 38791405 | 2024 | Apolipoprotein-CIII O-Glycosylation Is Associated with Micro- and Macrovascular Complications of Type 2 Diabetes. | 0 |
| 37972731 | 2024 | Apolipoprotein C3: form begets function. | 2 |
| 38039351 | 2024 | Exploring apolipoprotein C-III: pathophysiological and pharmacological relevance. | 1 |
| 38232538 | 2024 | Apolipoprotein C3 (ApoC3) facilitates NLRP3 mediated pyroptosis of macrophages through mitochondrial damage by accelerating of the interaction between SCIMP and SYK pathway in acute lung injury. | 0 |
| 38791405 | 2024 | Apolipoprotein-CIII O-Glycosylation Is Associated with Micro- and Macrovascular Complications of Type 2 Diabetes. | 0 |
| 36689070 | 2023 | APOC-III: a Gatekeeper in Controlling Triglyceride Metabolism. | 8 |
| 36855114 | 2023 | Apolipoprotein C3 is negatively associated with estrogen and mediates the protective effect of estrogen on hypertriglyceridemia in obese adults. | 1 |
| 36876364 | 2023 | APOC3 and ABCA1 variants in unusual combined hypolipidaemia showing premature peripheral vascular disease. | 0 |
| 36921196 | 2023 | Investigation of associations between apolipoprotein A5 and C3 gene polymorphisms with plasma triglyceride and lipid levels. | 0 |
| 37044204 | 2023 | Role of APOC3 3238C/G polymorphism in HIV-associated neurocognitive disorder. | 0 |
| 37866958 | 2023 | [Association Between Apolipoprotein C-3 SstⅠ Polymorphism and Serum Lipids in Patients With Gestational Diabetes Mellitus]. | 1 |
| 37902017 | 2023 | SP1 transcriptionally upregulates the expression of APOC3 in KGN cells to promote disease progression by regulating TLR2/NF-κB signalling pathway. | 0 |
Citation
Dessen P
APOC3 (apolipoprotein C3)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51037/apoc3-(apolipoprotein-c3)
