MB (myoglobin)

2009-08-01  

Identity

HGNC
LOCATION
22q12.3
LOCUSID
ALIAS
PVALB
FUSION GENES

Other Information

Locus ID:

NCBI: 4151
MIM: 160000
HGNC: 6915
Ensembl: ENSG00000198125

Variants:

dbSNP: 4151
ClinVar: 4151
TCGA: ENSG00000198125
COSMIC: MB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198125ENST00000359787P02144
ENSG00000198125ENST00000359787A0A1K0FU49
ENSG00000198125ENST00000397326P02144
ENSG00000198125ENST00000397326A0A1K0FU49
ENSG00000198125ENST00000397328P02144
ENSG00000198125ENST00000397328A0A1K0FU49
ENSG00000198125ENST00000401702Q8WVH6
ENSG00000198125ENST00000406324P02144
ENSG00000198125ENST00000406324A0A1K0FU49
ENSG00000198125ENST00000419229F2Z337
ENSG00000198125ENST00000442617B0QYF7
ENSG00000198125ENST00000443033B0QYF8
ENSG00000198125ENST00000447607F2Z2F1
ENSG00000198125ENST00000451685F2Z2F1

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000
7000
8000
9000

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
190051612009Hypoxia reprograms calcium signaling and regulates myoglobin expression.25
195419312009Expression and functional regulation of myoglobin in epithelial cancers.17
216404262011Neuroglobin and myoglobin in non-small cell lung cancer: expression, regulation and prognosis.17
173119972007Strong iron demand during hypoxia-induced erythropoiesis is associated with down-regulation of iron-related proteins and myoglobin in human skeletal muscle.16
205314162010Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype.11
219306972011Endogenous myoglobin in breast cancer is hypoxia-inducible by alternative transcription and functions to impair mitochondrial activity: a role in tumor suppression?11
176051152007Myoglobin plasma level related to muscle mass and fiber composition: a clinical marker of muscle wasting?10
239318772013Use of myoglobin as a marker and predictor in myoglobinuric acute kidney injury.10
156017592004Human myoglobin recognition of oxygen: dynamics of the energy landscape.9
232974022013Hydrophobic effect drives oxygen uptake in myoglobin via histidine E7.9

Citation

Dessen P

MB (myoglobin)

Atlas Genet Cytogenet Oncol Haematol. 2009-08-01

Online version: http://atlasgeneticsoncology.org/gene/51046/mb-(myoglobin)