RGMA (repulsive guidance molecule BMP co-receptor a)

2009-08-01  

Identity

HGNC
RGMA
LOCATION
15q26.1
LOCUSID
56963
ALIAS
RGM
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 56963
MIM: 607362
HGNC: 30308
Ensembl: ENSG00000182175

Variants:

dbSNP: 56963
ClinVar: 56963
TCGA: ENSG00000182175
COSMIC: RGMA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182175ENST00000329082Q96B86
ENSG00000182175ENST00000425933Q96B86
ENSG00000182175ENST00000542321Q96B86
ENSG00000182175ENST00000543599Q96B86
ENSG00000182175ENST00000554387G3V3Z3
ENSG00000182175ENST00000555598G3V4C2
ENSG00000182175ENST00000556658F5H7G2
ENSG00000182175ENST00000556950A0A0G2JL92
ENSG00000182175ENST00000557301A0A0A0MTQ4
ENSG00000182175ENST00000557420G3V545

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
Netrin-1 signalingREACTOMER-HSA-373752

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
387621922024Circular RNA circHIPK2 inhibits colon cancer cells through miR-373-3p/RGMA axis.0
387621922024Circular RNA circHIPK2 inhibits colon cancer cells through miR-373-3p/RGMA axis.0
350288892022Decreased DNA Methylation of RGMA is Associated with Intracranial Hypertension After Severe Traumatic Brain Injury: An Exploratory Epigenome-Wide Association Study.7
350288892022Decreased DNA Methylation of RGMA is Associated with Intracranial Hypertension After Severe Traumatic Brain Injury: An Exploratory Epigenome-Wide Association Study.7
339970002021Repulsive Guidance Molecule-a and Central Nervous System Diseases.4
339970002021Repulsive Guidance Molecule-a and Central Nervous System Diseases.4
318991582020MicroRNA-4472 Promotes Tumor Proliferation and Aggressiveness in Breast Cancer by Targeting RGMA and Inducing EMT.13
318991582020MicroRNA-4472 Promotes Tumor Proliferation and Aggressiveness in Breast Cancer by Targeting RGMA and Inducing EMT.13
307981202019Downregulation of RGMA by HIF-1A/miR-210-3p axis promotes cell proliferation in oral squamous cell carcinoma.18
307981202019Downregulation of RGMA by HIF-1A/miR-210-3p axis promotes cell proliferation in oral squamous cell carcinoma.18
294786982018Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.38
294786982018Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.38
288424192017Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease.14
288424192017Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease.14
267214392016Repulsive guidance molecule A suppresses angiogenesis.8

Citation

Dessen P

RGMA (repulsive guidance molecule BMP co-receptor a)

Atlas Genet Cytogenet Oncol Haematol. 2009-08-01

Online version: http://atlasgeneticsoncology.org/gene/51052/rgma-(repulsive-guidance-molecule-bmp-co-receptor-a)