Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2696
MIM: 137241
HGNC: 4271
Ensembl: ENSG00000010310
Variants:
dbSNP: 2696
ClinVar: 2696
TCGA: ENSG00000010310
COSMIC: GIPR
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation | associated | PD | 21747410, 25321336 | |
| PA450688 | olanzapine | Chemical | ClinicalAnnotation | associated | PD | 21747410, 25321336 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36774542 | 2023 | Enhanced Endosomal Signaling and Desensitization of GLP-1R vs GIPR in Pancreatic Beta Cells. | 5 |
| 36882778 | 2023 | Association of gastric inhibitory polypeptide receptor (GIPR) gene polymorphism with type 2 diabetes mellitus in iranian patients. | 2 |
| 37298217 | 2023 | The Methylation Analysis of the Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR) Locus in GH-Secreting Pituitary Adenomas. | 0 |
| 36774542 | 2023 | Enhanced Endosomal Signaling and Desensitization of GLP-1R vs GIPR in Pancreatic Beta Cells. | 5 |
| 36882778 | 2023 | Association of gastric inhibitory polypeptide receptor (GIPR) gene polymorphism with type 2 diabetes mellitus in iranian patients. | 2 |
| 37298217 | 2023 | The Methylation Analysis of the Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR) Locus in GH-Secreting Pituitary Adenomas. | 0 |
| 35065096 | 2022 | GLP-1 and GIP receptor signaling in beta cells - A review of receptor interactions and co-stimulation. | 22 |
| 36140702 | 2022 | The Link between Three Single Nucleotide Variants of the GIPR Gene and Metabolic Health. | 2 |
| 36177761 | 2022 | Differential effects of glucose-dependent insulinotropic polypeptide receptor/glucagon-like peptide-1 receptor heteromerization on cell signaling when expressed in HEK-293 cells. | 3 |
| 35065096 | 2022 | GLP-1 and GIP receptor signaling in beta cells - A review of receptor interactions and co-stimulation. | 22 |
| 36140702 | 2022 | The Link between Three Single Nucleotide Variants of the GIPR Gene and Metabolic Health. | 2 |
| 36177761 | 2022 | Differential effects of glucose-dependent insulinotropic polypeptide receptor/glucagon-like peptide-1 receptor heteromerization on cell signaling when expressed in HEK-293 cells. | 3 |
| 33290902 | 2021 | Targeting the GIPR for obesity: To agonize or antagonize? Potential mechanisms. | 40 |
| 33891864 | 2021 | Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor. | 7 |
| 34426508 | 2021 | Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region. | 9 |
Citation
Dessen P
GIPR (gastric inhibitory polypeptide receptor)
Atlas Genet Cytogenet Oncol Haematol. 2009-09-01
Online version: http://atlasgeneticsoncology.org/gene/51056/gipr-(gastric-inhibitory-polypeptide-receptor)
