Identity
HGNC
LOCATION
9q34.11
LOCUSID
ALIAS
C9orf15,GBF-1,GBF1,PGES2,mPGES-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80142
MIM: 608152
HGNC: 17822
Ensembl: ENSG00000148334
Variants:
dbSNP: 80142
ClinVar: 80142
TCGA: ENSG00000148334
COSMIC: PTGES2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000148334 | ENST00000277462 | A6NHH0 |
| ENSG00000148334 | ENST00000338961 | Q9H7Z7 |
| ENSG00000148334 | ENST00000449878 | X6RJ95 |
| ENSG00000148334 | ENST00000617202 | A6NHH0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38081591 | 2024 | Inhibiting cholesterol de novo synthesis promotes hepatocellular carcinoma progression by upregulating prostaglandin E synthase 2-mediated arachidonic acid metabolism under high fatty acid conditions. | 2 |
| 38081591 | 2024 | Inhibiting cholesterol de novo synthesis promotes hepatocellular carcinoma progression by upregulating prostaglandin E synthase 2-mediated arachidonic acid metabolism under high fatty acid conditions. | 2 |
| 31726220 | 2020 | Parasitic load determination by differential expressions of 5-lipoxygenase and PGE2 synthases in visceral leishmaniasis. | 6 |
| 31726220 | 2020 | Parasitic load determination by differential expressions of 5-lipoxygenase and PGE2 synthases in visceral leishmaniasis. | 6 |
| 31113465 | 2019 | Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. | 37 |
| 31113465 | 2019 | Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. | 37 |
| 24467603 | 2014 | Genetic variation in the prostaglandin E2 pathway is associated with primary graft dysfunction. | 17 |
| 24467603 | 2014 | Genetic variation in the prostaglandin E2 pathway is associated with primary graft dysfunction. | 17 |
| 19664621 | 2010 | Microsomal prostaglandin E synthase-2: cellular distribution and expression in Alzheimer's disease. | 15 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 19664621 | 2010 | Microsomal prostaglandin E synthase-2: cellular distribution and expression in Alzheimer's disease. | 15 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 19268562 | 2009 | Influence of a type 2 diabetes associated prostaglandin E synthase 2 polymorphism on blood prostaglandin E2 levels. | 3 |
| 19336370 | 2009 | Determination of genetic predisposition to patent ductus arteriosus in preterm infants. | 27 |
| 19347995 | 2009 | The terminal prostaglandin synthases mPGES-1, mPGES-2, and cPGES are all overexpressed in human gliomas. | 21 |
Citation
Dessen P
PTGES2 (prostaglandin E synthase 2)
Atlas Genet Cytogenet Oncol Haematol. 2009-09-01
Online version: http://atlasgeneticsoncology.org/gene/51067/ptges2-(prostaglandin-e-synthase-2)
