CDH22 (cadherin 22)

2009-09-01  

Identity

HGNC
LOCATION
20q13.12
LOCUSID
ALIAS
C20orf25,dJ998H6.1
FUSION GENES

Other Information

Locus ID:

NCBI: 64405
MIM: 609920
HGNC: 13251
Ensembl: ENSG00000149654

Variants:

dbSNP: 64405
ClinVar: 64405
TCGA: ENSG00000149654
COSMIC: CDH22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149654ENST00000537909Q9UJ99

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
186029832008Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1.16
86267161996Molecular cloning and characterization of a newly identified member of the cadherin family, PB-cadherin.15
206503122010Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.15
194400362009PRL-3 promotes epithelial mesenchymal transition by regulating cadherin directly.12
195466062009Over-expression of CDH22 is associated with tumor progression in colorectal cancer.9
289912292018Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion.7
281493352017CDH22 hypermethylation is an independent prognostic biomarker in breast cancer.2

Citation

Dessen P

CDH22 (cadherin 22)

Atlas Genet Cytogenet Oncol Haematol. 2009-09-01

Online version: http://atlasgeneticsoncology.org/gene/51088/cdh22-(cadherin-22)