Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11091
MIM: 609012
HGNC: 12757
Ensembl: ENSG00000196363
Variants:
dbSNP: 11091
ClinVar: 11091
TCGA: ENSG00000196363
COSMIC: WDR5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000196363 | ENST00000358625 | P61964 |
| ENSG00000196363 | ENST00000608739 | V9GZ59 |
| ENSG00000196363 | ENST00000608937 | V9GYQ5 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38547933 | 2024 | METTL3 orchestrates glycolysis by stabilizing the c-Myc/WDR5 complex in triple-negative breast cancer. | 0 |
| 38605297 | 2024 | Mitotic gene regulation by the N-MYC-WDR5-PDPK1 nexus. | 0 |
| 38744853 | 2024 | The NTE domain of PTENα/β promotes cancer progression by interacting with WDR5 via its SSSRRSS motif. | 0 |
| 38547933 | 2024 | METTL3 orchestrates glycolysis by stabilizing the c-Myc/WDR5 complex in triple-negative breast cancer. | 0 |
| 38605297 | 2024 | Mitotic gene regulation by the N-MYC-WDR5-PDPK1 nexus. | 0 |
| 38744853 | 2024 | The NTE domain of PTENα/β promotes cancer progression by interacting with WDR5 via its SSSRRSS motif. | 0 |
| 36324256 | 2023 | miR-101-3p contributes to the progression of preeclampsia by suppressing WDR5-mediated proliferation and invasion of trophoblast. | 3 |
| 36408368 | 2023 | A clustering of heterozygous missense variants in the crucial chromatin modifier WDR5 defines a new neurodevelopmental disorder. | 4 |
| 36409397 | 2023 | Intermittent hypoxia BMSCs-derived exosomal miR-31-5p promotes lung adenocarcinoma development via WDR5-induced epithelial mesenchymal transition. | 0 |
| 37021550 | 2023 | WDR5 is required for DUX4 expression and its pathological effects in FSHD muscular dystrophy. | 1 |
| 37725512 | 2023 | Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5. | 5 |
| 37852994 | 2023 | MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1. | 1 |
| 38055397 | 2023 | WD repeat domain 5 promotes the development of late-onset preeclampsia by activating nuclear factor kappa B. | 0 |
| 36324256 | 2023 | miR-101-3p contributes to the progression of preeclampsia by suppressing WDR5-mediated proliferation and invasion of trophoblast. | 3 |
| 36408368 | 2023 | A clustering of heterozygous missense variants in the crucial chromatin modifier WDR5 defines a new neurodevelopmental disorder. | 4 |
Citation
Dessen P
WDR5 (WD repeat domain 5)
Atlas Genet Cytogenet Oncol Haematol. 2009-09-01
Online version: http://atlasgeneticsoncology.org/gene/51091/wdr5-(wd-repeat-domain-5)
