Identity
HGNC
LOCATION
1p36.12
LOCUSID
ALIAS
AOF2,BHC110,CPRF,KDM1,LSD1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23028
MIM: 609132
HGNC: 29079
Ensembl: ENSG00000004487
Variants:
dbSNP: 23028
ClinVar: 23028
TCGA: ENSG00000004487
COSMIC: KDM1A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000004487 | ENST00000356634 | O60341 |
| ENSG00000004487 | ENST00000400181 | O60341 |
| ENSG00000004487 | ENST00000465864 | R4GMQ1 |
| ENSG00000004487 | ENST00000494920 | R4GMP9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38151469 | 2024 | Uncovering New Conformational States of the Substrate Binding Pocket of LSD1 Potential for Inhibitor Design via Funnel Metadynamics. | 0 |
| 38152966 | 2024 | LSD1 Regulates Neurogenesis in Human Neural Stem Cells Through the Repression of Human-Enriched Extracellular Matrix and Cell Adhesion Genes. | 0 |
| 38286920 | 2024 | DUSP4 maintains the survival and LSD1 protein stability in esophageal squamous cell carcinoma cells by inhibiting JNK signaling-dependent autophagy. | 0 |
| 38295985 | 2024 | Histone demethylase KDM1A promotes hepatic steatosis and inflammation by increasing chromatin accessibility in NAFLD. | 0 |
| 38315842 | 2024 | RNF20 contributes to epigenetic immunosuppression through CDK9-dependent LSD1 stabilization. | 1 |
| 38461301 | 2024 | TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells. | 0 |
| 38548886 | 2024 | GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation. | 0 |
| 38965210 | 2024 | Transposable elements-mediated recruitment of KDM1A epigenetically silences HNF4A expression to promote hepatocellular carcinoma. | 0 |
| 38151469 | 2024 | Uncovering New Conformational States of the Substrate Binding Pocket of LSD1 Potential for Inhibitor Design via Funnel Metadynamics. | 0 |
| 38152966 | 2024 | LSD1 Regulates Neurogenesis in Human Neural Stem Cells Through the Repression of Human-Enriched Extracellular Matrix and Cell Adhesion Genes. | 0 |
| 38286920 | 2024 | DUSP4 maintains the survival and LSD1 protein stability in esophageal squamous cell carcinoma cells by inhibiting JNK signaling-dependent autophagy. | 0 |
| 38295985 | 2024 | Histone demethylase KDM1A promotes hepatic steatosis and inflammation by increasing chromatin accessibility in NAFLD. | 0 |
| 38315842 | 2024 | RNF20 contributes to epigenetic immunosuppression through CDK9-dependent LSD1 stabilization. | 1 |
| 38461301 | 2024 | TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells. | 0 |
| 38548886 | 2024 | GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation. | 0 |
Citation
Dessen P
KDM1A (lysine demethylase 1A)
Atlas Genet Cytogenet Oncol Haematol. 2009-10-01
Online version: http://atlasgeneticsoncology.org/gene/51150
