SLC2A12 (solute carrier family 2 member 12)

2009-10-01  

Identity

HGNC
LOCATION
6q23.2
LOCUSID
ALIAS
GLUT12,GLUT8
FUSION GENES

Other Information

Locus ID:

NCBI: 154091
MIM: 610372
HGNC: 18067
Ensembl: ENSG00000146411

Variants:

dbSNP: 154091
ClinVar: 154091
TCGA: ENSG00000146411
COSMIC: SLC2A12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146411ENST00000275230Q8TD20

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Facilitative Na+-independent glucose transportersREACTOMER-HSA-428790

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
125835992002Placental glucose transfer and fetal growth.41
195497452009Insulin-stimulated translocation of glucose transporter (GLUT) 12 parallels that of GLUT4 in normal muscle.38
207340642010A large-scale candidate gene association study of age at menarche and age at natural menopause.38
233969692013Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8.31
168038532006Hexose transporter mRNAs for GLUT4, GLUT5, and GLUT12 predominate in human muscle.30
189786782008Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.21
233027802013Expression of conventional and novel glucose transporters, GLUT1, -9, -10, and -12, in vascular smooth muscle cells.21
129147652003Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes.19
128904772003Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues.15
160915812006Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy.12

Citation

Dessen P

SLC2A12 (solute carrier family 2 member 12)

Atlas Genet Cytogenet Oncol Haematol. 2009-10-01

Online version: http://atlasgeneticsoncology.org/gene/51172/slc2a12-(solute-carrier-family-2-member-12)