MIR20A (microRNA 20a)

2009-11-01  

Identity

HGNC
LOCATION
13q31.3
LOCUSID
ALIAS
C13orf25,MIR17HG,MIR20,MIRH1,MIRHG1,MIRN20,MIRN20A,hsa-mir-20,hsa-mir-20a,miR-20,miRNA20A,mir-20a

Other Information

Locus ID:

NCBI: 406982
MIM: 609420
HGNC: 31577
Ensembl: ENSG00000283762
miRBase:

Variants:

dbSNP: 406982
ClinVar: 406982
TCGA: ENSG00000283762
COSMIC: MIR20A

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
159447092005c-Myc-regulated microRNAs modulate E2F1 expression.1081
171352492007An E2F/miR-20a autoregulatory feedback loop.238
226827612012The structure of human argonaute-2 in complex with miR-20a.186
186950422008A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation.161
186326052008Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster.119
198936192009Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration.80
188364832009miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression.72
221861402012miR-20a encoded by the miR-17-92 cluster increases the metastatic potential of osteosarcoma cells by regulating Fas expression.66
212837652011MicroRNAs MiR-17, MiR-20a, and MiR-106b act in concert to modulate E2F activity on cell cycle arrest during neuronal lineage differentiation of USSC.55
227515002012STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA.49

Citation

Dessen P

MIR20A (microRNA 20a)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51173/mir20a-(microrna-20a)