ZBTB2 (zinc finger and BTB domain containing 2)

2009-11-01  

Identity

HGNC
LOCATION
6q25.1
LOCUSID
ALIAS
ZNF437
FUSION GENES

Other Information

Locus ID:

NCBI: 57621
MIM: 616595
HGNC: 20868
Ensembl: ENSG00000181472

Variants:

dbSNP: 57621
ClinVar: 57621
TCGA: ENSG00000181472
COSMIC: ZBTB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181472ENST00000325144Q8N680

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
363415212023ZBTB2 links p53 deficiency to HIF-1-mediated hypoxia signaling to promote cancer aggressiveness.1
372577722023ZBTB2 is Recruited to a Specific Subset of HIF-1 Target Loci to Facilitate Full Gene Expression Under Hypoxia.1
363415212023ZBTB2 links p53 deficiency to HIF-1-mediated hypoxia signaling to promote cancer aggressiveness.1
372577722023ZBTB2 is Recruited to a Specific Subset of HIF-1 Target Loci to Facilitate Full Gene Expression Under Hypoxia.1
333018492021ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.2
333018492021ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.2
319707742020MiR-4282 inhibits tumor progression through down-regulation of ZBTB2 by targeting LIN28B in oral squamous cell carcinoma.6
321965942020OIP5-AS1 promotes the progression of gastric cancer cells via the miR-153-3p/ZBTB2 axis.9
319707742020MiR-4282 inhibits tumor progression through down-regulation of ZBTB2 by targeting LIN28B in oral squamous cell carcinoma.6
321965942020OIP5-AS1 promotes the progression of gastric cancer cells via the miR-153-3p/ZBTB2 axis.9
312438062019MicroRNA-488-3p inhibits proliferation and induces apoptosis by targeting ZBTB2 in esophageal squamous cell carcinoma.13
312438062019MicroRNA-488-3p inhibits proliferation and induces apoptosis by targeting ZBTB2 in esophageal squamous cell carcinoma.13
301773882018LncRNA CALML3-AS1 promotes tumorigenesis of bladder cancer via regulating ZBTB2 by suppression of microRNA-4316.16
301773882018LncRNA CALML3-AS1 promotes tumorigenesis of bladder cancer via regulating ZBTB2 by suppression of microRNA-4316.16
256096942015ZBTB2 increases PDK4 expression by transcriptional repression of RelA/p65.17

Citation

Dessen P

ZBTB2 (zinc finger and BTB domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51184/zbtb2