Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55506
MIM: 616141
HGNC: 14453
Ensembl: ENSG00000099284
Variants:
dbSNP: 55506
ClinVar: 55506
TCGA: ENSG00000099284
COSMIC: MACROH2A2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000099284 | ENST00000373255 | Q9P0M6 |
| ENSG00000099284 | ENST00000373255 | A0A024QZP6 |
| ENSG00000099284 | ENST00000455786 | Q5SQT3 |
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Systemic lupus erythematosus | KEGG | ko05322 |
| Systemic lupus erythematosus | KEGG | hsa05322 |
| Alcoholism | KEGG | hsa05034 |
| Alcoholism | KEGG | ko05034 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38251858 | 2024 | Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF-κB pathway, and elevated MMP13 expression. | 0 |
| 38251858 | 2024 | Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF-κB pathway, and elevated MMP13 expression. | 0 |
| 35072799 | 2022 | Analysis of histone variant constraint and tissue expression suggests five potential novel human disease genes: H2AFY2, H2AFZ, H2AFY, H2AFV, H1F0. | 3 |
| 35072799 | 2022 | Analysis of histone variant constraint and tissue expression suggests five potential novel human disease genes: H2AFY2, H2AFZ, H2AFY, H2AFV, H1F0. | 3 |
| 34223906 | 2021 | LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2. | 12 |
| 34223906 | 2021 | LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2. | 12 |
| 29654602 | 2019 | A genome wide association study identifies new genes potentially associated with eyelid sagging. | 5 |
| 29654602 | 2019 | A genome wide association study identifies new genes potentially associated with eyelid sagging. | 5 |
| 30177554 | 2018 | MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms. | 36 |
| 30177554 | 2018 | MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms. | 36 |
| 20080650 | 2010 | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. | 57 |
| 20080650 | 2010 | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. | 57 |
| 19648962 | 2009 | Histone macroH2A isoforms predict the risk of lung cancer recurrence. | 99 |
| 19648962 | 2009 | Histone macroH2A isoforms predict the risk of lung cancer recurrence. | 99 |
| 16385451 | 2006 | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. | 83 |
Citation
Dessen P
MACROH2A2 (macroH2A.2 histone)
Atlas Genet Cytogenet Oncol Haematol. 2009-11-01
Online version: http://atlasgeneticsoncology.org/gene/51204/macroh2a2-(macroh2a-2-histone)
