MSL1 (MSL complex subunit 1)

2009-11-01  

Identity

HGNC
LOCATION
17q21.1
LOCUSID
ALIAS
MSL-1
FUSION GENES

Other Information

Locus ID:

NCBI: 339287
MIM: 614801
HGNC: 27905
Ensembl: ENSG00000188895

Variants:

dbSNP: 339287
ClinVar: 339287
TCGA: ENSG00000188895
COSMIC: MSL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188895ENST00000398532Q68DK7
ENSG00000188895ENST00000577454J3QQY0
ENSG00000188895ENST00000578648J3KSZ8
ENSG00000188895ENST00000579565Q68DK7
ENSG00000188895ENST00000582884J3KTC2
ENSG00000188895ENST00000582920J3KRQ4

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
162275712005A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16.139
196500742009p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage.17
242051102013Deciphering the binding between Nupr1 and MSL1 and their DNA-repairing activity.10
249139092014Two distinct nuclear localization signals in mammalian MSL1 regulate its function.0

Citation

Dessen P

MSL1 (MSL complex subunit 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51219/msl1-(msl-complex-subunit-1)