BNC2 (basonuclin 2)

2009-11-01  

Identity

HGNC
BNC2
LOCATION
9p22.3
LOCUSID
54796
ALIAS
BSN2,LUTO
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54796
MIM: 608669
HGNC: 30988
Ensembl: ENSG00000173068

Variants:

dbSNP: 54796
ClinVar: 54796
TCGA: ENSG00000173068
COSMIC: BNC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173068ENST00000380666A0A1B0GX98
ENSG00000173068ENST00000380667B1APH0
ENSG00000173068ENST00000380672Q6ZN30
ENSG00000173068ENST00000411752H0Y4J1
ENSG00000173068ENST00000418777H0Y6W5
ENSG00000173068ENST00000468187S4R3K9
ENSG00000173068ENST00000471301S4R3X5
ENSG00000173068ENST00000484726Q6ZN30
ENSG00000173068ENST00000486514S4R3R8
ENSG00000173068ENST00000545497F5H586
ENSG00000173068ENST00000603313S4R351
ENSG00000173068ENST00000603713Q06HB9
ENSG00000173068ENST00000613349Q06HC7
ENSG00000173068ENST00000617779Q06HC7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
375369772023Basonuclin-2 regulates extracellular matrix production and degradation.0
375369772023Basonuclin-2 regulates extracellular matrix production and degradation.0
360884592022Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis.11
360884592022Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis.11
331797412021Genomic characterization of the adolescent idiopathic scoliosis-associated transcriptome and regulome.8
331797412021Genomic characterization of the adolescent idiopathic scoliosis-associated transcriptome and regulome.8
310511152019Rare Variants in BNC2 Are Implicated in Autosomal-Dominant Congenital Lower Urinary-Tract Obstruction.16
310511152019Rare Variants in BNC2 Are Implicated in Autosomal-Dominant Congenital Lower Urinary-Tract Obstruction.16
295493622018An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis.10
295493622018An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis.10
283420422017Genetic variant of BNC2 gene is functionally associated with adolescent idiopathic scoliosis in Chinese population.6
283420422017Genetic variant of BNC2 gene is functionally associated with adolescent idiopathic scoliosis in Chinese population.6
268210132016Decreased Expression of BNC1 and BNC2 Is Associated with Genetic or Epigenetic Regulation in Hepatocellular Carcinoma.8
278998182016BNC2 is a putative tumor suppressor gene in high-grade serous ovarian carcinoma and impacts cell survival after oxidative stress.12
268210132016Decreased Expression of BNC1 and BNC2 Is Associated with Genetic or Epigenetic Regulation in Hepatocellular Carcinoma.8

Citation

Dessen P

BNC2 (basonuclin 2)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51224/bnc2-(basonuclin-2)