Identity
HGNC
LOCATION
14q31.1
LOCUSID
ALIAS
TF2A1,TFIIA,TFIIA-42,TFIIAL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2957
MIM: 600520
HGNC: 4646
Ensembl: ENSG00000165417
Variants:
dbSNP: 2957
ClinVar: 2957
TCGA: ENSG00000165417
COSMIC: GTF2A1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165417 | ENST00000298173 | J3KNC0 |
| ENSG00000165417 | ENST00000434192 | P52655 |
| ENSG00000165417 | ENST00000553612 | P52655 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28992066 | 2018 | TFIIA transcriptional activity is controlled by a 'cleave-and-run' Exportin-1/Taspase 1-switch. | 4 |
| 28992066 | 2018 | TFIIA transcriptional activity is controlled by a 'cleave-and-run' Exportin-1/Taspase 1-switch. | 4 |
| 28291257 | 2017 | Integrated transcriptome and methylome analysis in youth at high risk for bipolar disorder: a preliminary analysis. | 11 |
| 28539359 | 2017 | A transcription factor IIA-binding site differentially regulates RNA polymerase II-mediated transcription in a promoter context-dependent manner. | 9 |
| 29097782 | 2017 | Disease-relevant signalling-pathways in head and neck cancer: Taspase1's proteolytic activity fine-tunes TFIIA function. | 5 |
| 28291257 | 2017 | Integrated transcriptome and methylome analysis in youth at high risk for bipolar disorder: a preliminary analysis. | 11 |
| 28539359 | 2017 | A transcription factor IIA-binding site differentially regulates RNA polymerase II-mediated transcription in a promoter context-dependent manner. | 9 |
| 29097782 | 2017 | Disease-relevant signalling-pathways in head and neck cancer: Taspase1's proteolytic activity fine-tunes TFIIA function. | 5 |
| 27696626 | 2016 | Ubiquitin-proteasome-dependent degradation of TBP-like protein is prevented by direct binding of TFIIA. | 0 |
| 27696626 | 2016 | Ubiquitin-proteasome-dependent degradation of TBP-like protein is prevented by direct binding of TFIIA. | 0 |
| 25996597 | 2015 | Taspase1 processing alters TFIIA cofactor properties in the regulation of TFIID. | 5 |
| 25996597 | 2015 | Taspase1 processing alters TFIIA cofactor properties in the regulation of TFIID. | 5 |
| 18950845 | 2009 | Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. | 5 |
| 19724865 | 2009 | Identification of candidate epigenetic biomarkers for ovarian cancer detection. | 11 |
| 18950845 | 2009 | Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. | 5 |
Citation
Dessen P
GTF2A1 (general transcription factor IIA subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-11-01
Online version: http://atlasgeneticsoncology.org/gene/51238/gtf2a1-(general-transcription-factor-iia-subunit-1)
