MBP (myelin basic protein)

2010-01-01  

Identity

HGNC
LOCATION
18q23
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 4155
MIM: 159430
HGNC: 6925
Ensembl: ENSG00000197971

Variants:

dbSNP: 4155
ClinVar: 4155
TCGA: ENSG00000197971
COSMIC: MBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197971ENST00000354542F8WEU6
ENSG00000197971ENST00000355994P02686
ENSG00000197971ENST00000355994A0A024R384
ENSG00000197971ENST00000359645P02686
ENSG00000197971ENST00000382582P02686
ENSG00000197971ENST00000397860P02686
ENSG00000197971ENST00000397863P02686
ENSG00000197971ENST00000397865P02686
ENSG00000197971ENST00000397866P02686
ENSG00000197971ENST00000397869H7BYR8
ENSG00000197971ENST00000397875A8MZH3
ENSG00000197971ENST00000447114C9J6H1
ENSG00000197971ENST00000459948H0YEA2
ENSG00000197971ENST00000473302E9PMR5
ENSG00000197971ENST00000483025F5H7N4
ENSG00000197971ENST00000493623H0YF02
ENSG00000197971ENST00000498683E9PNZ1
ENSG00000197971ENST00000526111E9PJ72
ENSG00000197971ENST00000527041E9PKX9
ENSG00000197971ENST00000527975E9PLU9
ENSG00000197971ENST00000528160E9PQE7
ENSG00000197971ENST00000531144E9PLQ9
ENSG00000197971ENST00000533278E9PSE2
ENSG00000197971ENST00000577755J3KT34
ENSG00000197971ENST00000578193J3QL64
ENSG00000197971ENST00000578873J3QKL5
ENSG00000197971ENST00000579129J3QQK6
ENSG00000197971ENST00000580402P02686
ENSG00000197971ENST00000580402A0A024R384
ENSG00000197971ENST00000581878J3KS94
ENSG00000197971ENST00000583474E9PLQ9
ENSG00000197971ENST00000583798J3QKN5
ENSG00000197971ENST00000585201J3KT01

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000
7000
8000
9000
10000

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
150096772004Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin.81
186631242008EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-gamma and IL-2.57
173511122007EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression.55
178232882007p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy.52
218600872011Cerebrospinal fluid matrix metalloproteinases and tissue inhibitor of metalloproteinases in combination with subcortical and cortical biomarkers in vascular dementia and Alzheimer's disease.48
191102652009Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia.43
204710302010Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia.42
163878492006Autoantibodies to myelin basic protein catalyze site-specific degradation of their antigen.39
190343802009Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis.36
188020672008Swift entry of myelin-specific T lymphocytes into the central nervous system in spontaneous autoimmune encephalomyelitis.32

Citation

Dessen P

MBP (myelin basic protein)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51260/mbp-(myelin-basic-protein)