Identity
HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
PR-Set7,PR/SET07,SET07,SET8,SETD8
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 387893
MIM: 607240
HGNC: 29489
Ensembl: ENSG00000183955
Variants:
dbSNP: 387893
ClinVar: 387893
TCGA: ENSG00000183955
COSMIC: KMT5A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183955 | ENST00000330479 | A0A0C4DFR3 |
| ENSG00000183955 | ENST00000402868 | Q9NQR1 |
| ENSG00000183955 | ENST00000437502 | C9JKQ0 |
| ENSG00000183955 | ENST00000437519 | F8WC45 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38301049 | 2024 | Interaction of Sp1 and Setd8 promotes vascular smooth muscle cells apoptosis by activating Mark4 in vascular calcification. | 1 |
| 38565081 | 2024 | Lysine Methyltransferase 5A Promotes the Progression of Growth Hormone Pituitary Neuroendocrine Tumors through the Wnt/β-Catenin Signaling Pathway. | 0 |
| 38963044 | 2024 | Inhibition of FBP1 expression by KMT5A through TWIST1 methylation is one of the mechanisms leading to chemoresistance in breast cancer. | 0 |
| 38301049 | 2024 | Interaction of Sp1 and Setd8 promotes vascular smooth muscle cells apoptosis by activating Mark4 in vascular calcification. | 1 |
| 38565081 | 2024 | Lysine Methyltransferase 5A Promotes the Progression of Growth Hormone Pituitary Neuroendocrine Tumors through the Wnt/β-Catenin Signaling Pathway. | 0 |
| 38963044 | 2024 | Inhibition of FBP1 expression by KMT5A through TWIST1 methylation is one of the mechanisms leading to chemoresistance in breast cancer. | 0 |
| 36921492 | 2023 | SETD8 promotes glycolysis in colorectal cancer via regulating HIF1α/HK2 axis. | 0 |
| 36921492 | 2023 | SETD8 promotes glycolysis in colorectal cancer via regulating HIF1α/HK2 axis. | 0 |
| 34846946 | 2022 | SET8, a novel regulator to ameliorate vascular calcification via activating PI3K/Akt mediated anti-apoptotic effects. | 4 |
| 34894606 | 2022 | Integrative bioinformatics analysis the clinical value of KMT5A in different subtypes of lung cancer. | 0 |
| 35449131 | 2022 | KMT5A-methylated SNIP1 promotes triple-negative breast cancer metastasis by activating YAP signaling. | 10 |
| 36149050 | 2022 | KMT5A Knockdown Suppresses Osteosarcoma Cell Proliferation and Metastasis Through Ꞵ-Catenin Signalling. | 3 |
| 34846946 | 2022 | SET8, a novel regulator to ameliorate vascular calcification via activating PI3K/Akt mediated anti-apoptotic effects. | 4 |
| 34894606 | 2022 | Integrative bioinformatics analysis the clinical value of KMT5A in different subtypes of lung cancer. | 0 |
| 35449131 | 2022 | KMT5A-methylated SNIP1 promotes triple-negative breast cancer metastasis by activating YAP signaling. | 10 |
Citation
Dessen P
KMT5A (lysine methyltransferase 5A)
Atlas Genet Cytogenet Oncol Haematol. 2015-11-01
Online version: http://atlasgeneticsoncology.org/gene/51291/kmt5a-(lysine-methyltransferase-5a)
